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TranscriptomicsCritical role of the hydrogen peroxide-responsive nuclear kinase CK1-alpha-LS in vascular cell activation
CK1-alpha-LS was knocked down in human coronary artery smooth muscle cells. Gene level and exon level changes in expression were assessed. CK1-alpha-LS was knocked down in human coronary artery smooth muscle cells using retrovirus containing shRNA targeting the alternatively spliced L-insert.
ORGANISM(S): Homo sapiens 
2010-12-11 | E-GEOD-19441 | biostudies-arrayexpress
TranscriptomicsCritical role of the hydrogen peroxide-responsive nuclear kinase CK1-alpha-LS in vascular cell activation
CK1-alpha-LS was knocked down in human coronary artery smooth muscle cells. Gene level and exon level changes in expression were assessed.
ORGANISM(S): Homo sapiens 
2010-12-11 | GSE19441 | GEO
TranscriptomicsIdentification of gene expression changes in MEF cell lines with a targeted MDMX mutation that disrupts binding to CK1-alpha kinase
The goal of this experiment is to identify genes differentially expressed in MEF cell lines with a targeted MDMX mutation that prevents binding and inhibition of CK1-alpha kinase.
ORGANISM(S): Mus musculus 
2020-04-07 | GSE148138 | GEO
GenomicsIdentification of gene expression changes in MEF cell lines with a targeted MDMX mutation that disrupts binding to CK1-alpha kinase
Identification of gene expression changes in MEF cell lines with a targeted MDMX mutation that disrupts binding to CK1-alpha kinase
PRJNA623334 | ENA
GenomicsHomo sapiens
Critical role of the hydrogen peroxide-responsive nuclear kinase CK1-alpha-LS in vascular cell activation
PRJNA122313 | ENA
ProteomicsCrbnI391V is sufficient to confer in vivo sensitivity to thalidomide derivatives in mice
Fink EC, McConkey M, Adams DN, Haldar SD, Guirguis A, Udeshi ND, Kennedy JA, Mani DR, Chen M, Svinkina T, Nguyen A, Carr SA, and Ebert BL. Blood 2018. Thalidomide, infamous for its teratogenic effects, and derivatives lenalidomide and pomalidomide have found new clinical utility as treatments for mu...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2018-07-23 | MSV000082653 | MassIVE
ProteomicsThe FAM83 family of proteins are anchors for Casein Kinase 1 isoforms through the DUF1669 domain
The Casein Kinase 1 (CK1) family of Ser/Thr protein kinases are implicated in the regulation of many cellular processes, including cell cycle, circadian rhythm, Wnt and Sonic Hedgehog signalling. Regarded as constitutively active kinases, their regulation in cells is critically important but poorly ...
ORGANISM(S): Homo sapiens (Human) 
2018-05-24 | PXD009335 | Pride
Fam83 proteomics 
ProteomicsHuman CK1 alpha (CK1α) 5'UTR-interacting proteins
We used tobramycin-affinity RNA-pulldown assays coupled with mass spectrometry to identify CK1α 5'-UTR-binding proteins.
ORGANISM(S): Homo sapiens (Human) 
2022-10-01 | PXD027124 | Pride
Cancer Ck1a Ras Translation 
UnknownA noncanonical sequence phosphorylated by casein kinase 1 in beta-catenin may play a role in casein kinase 1 targeting of important signaling proteins.
Not available
S-EPMC193538 | biostudies-literature
UnknownThe DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms.
Not available
S-EPMC6025793 | biostudies-literature
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