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TranscriptomicsExpression data of cHL cell lines after KLF4 activation
Characteristic extinguishing of B-cell phenotype in cHL is believed to be a result of transcription factor network deregulation due to the overexpression of repressor proteins ID2 and ABF-1. KLF4 is a versatile transcription factor, participating in regulation of differentiation processes in various...
ORGANISM(S): Homo sapiens 
2010-10-22 | E-GEOD-21296 | biostudies-arrayexpress
MetabolomicsMetabolic alterations in pea leaves during arbuscular mycorrhiza development

Arbuscular mycorrhiza (AM) is known to be a mutually beneficial plant-fungal symbiosis; however, the effect of mycorrhization is heavily dependent on multiple biotic and abiotic factors. Therefore, for the proper employment of such plant-fungal symbiotic systems in agriculture, a detailed underst...

2020-02-09 | MTBLS893 | MetaboLights
TranscriptomicsExpression data of cHL cell lines after FOXO1 activation
FOXO1 is highly expressed in normal B cells and in most types of non-Hodgkinl lymphoma. In Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma(cHL) expression of FOXO1 is low or absent. We overexpressed constitutively active mutant of FOXO1 fused in frame with estrogen receptor ligand-bin...
ORGANISM(S): Homo sapiens 
2012-05-31 | E-GEOD-29545 | biostudies-arrayexpress
TranscriptomicsAffymetrix whole transcriptome gene expression analysis of ER-stressed Jurkat cells
We induced ER stress in Jurkat T-cells with dithiothreitol (DTT), which reduces the protein disulfide bonds and causes the accumulation of misfolded proteins in the ER lumen. For assessment of DTT effects on cells, we performed Affymetrix whole transcriptome gene expression analysis. The cells were ...
ORGANISM(S): Homo sapiens 
2017-04-15 | E-MTAB-5574 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse inflammatory response to titanium dioxide particles exposure is enhanced during pregnancy
Rationale: Maternal immune responses can promote allergy development in offspring. Pilot data show that neonates of mother mice exposed during pregnancy to air pollution particles have increased allergic susceptibility. Objective: We investigated whether inflammatory response to titanium dioxide (Ti...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7475 | biostudies-arrayexpress
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