Sort   by:  
 Page size 
TranscriptomicsThe bone marrow microenvironment in patients with neuroblastoma: presence of IFN signature and significant down-regulation of CXCL12 expression
Neuroblastoma (NB) is the most common extra cranial solid tumor in infants. Although several risk factors including patient age, disease stage and genetic abnormalities, such as MYCN amplification and 11q deletion, have been shown to predict outcome, the mechanisms responsible for the heterogeneous ...
ORGANISM(S): Homo sapiens 
2011-09-29 | E-GEOD-25624 | biostudies-arrayexpress
TranscriptomicsPromoter hypermethylation in MLL-r leukemia: biology and therapeutic targeting
MLL-r infant acute lymphoblastic leukemia (ALL) has largely unclear oncogenesis. It has been shown unrelated to copy number change or mutations in the tyrosine kinome. We therefore, explored the possible role of genome wide CpG island hypermethylation in MLL-r infant ALL. We employed the HpaII-ti...
ORGANISM(S): Homo sapiens 
2009-12-29 | E-GEOD-19671 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of rat kidney from animals with low, normal or high blood pressure
Hypertensive congenic kidney - 21 week Salt RAE230A and B
ORGANISM(S): Rattus norvegicus 
2007-06-22 | E-MIMR-541 | biostudies-arrayexpress
TranscriptomicsExpression data of Soybean (Glycine max) roots from different iron treatments.
Two Near Isogenic soybean (Glycine max) lines were grown in hydroponic conditions with either 50uM ferric nitrate or 100uM ferric nitrate. After 10 days, half the plants were harvested (total root tissue). At 12 days after planting, iron was added to plants grown in low iron conditions bringing th...
ORGANISM(S): Glycine max 
2010-09-06 | E-GEOD-22227 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Cornelia de Lange Syndrome proband derived cell lines reveals defective cohesin in cdls mediates gene expression with characteristics of transcription factor and insulator activity
The Cohesin apparatus has a canonical role in sister chromatid cohesion. Heterozygous mutations in Nipped B-like (NIPBL), SMC1A, and SMC3 have been found in 60% of probands with Cornelia de Lange Syndrome (CdLS), a dominant multi-system genetic disorder with variable expression. We have performed a ...
ORGANISM(S): Homo sapiens 
2009-06-08 | E-GEOD-12408 | biostudies-arrayexpress
TranscriptomicsGenome wide DNA Methylation Study in Cornelia de Lange Syndrome
Differential DNA methylation was identified in CdLS, and correlates to cohesin binding as well. However, DNA methylation may only be one of several events that regulate gene expression in humans. 63 Lymphoblastoid cell lines (LCLs) from 39 CdLS probands, 2 RBS probands and 22 gender and racial match...
ORGANISM(S): Homo sapiens 
2010-07-07 | E-GEOD-18458 | biostudies-arrayexpress
TranscriptomicsBlood mRNA expression signatures derived from unsupervised analyses identify prostate cancers with poor outcome
Background: Inter-patient prostate cancer (PrCa) heterogeneity results in highly variable patient outcomes. Multi-purpose biomarkers to dissect this heterogeneity are urgently required to improve treatment and accelerate drug development in PrCa. Circulating biomarkers are most practical for evaluat...
ORGANISM(S): Homo sapiens 
2012-10-15 | E-GEOD-37199 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of RNA stability in mouse Neuro-2A cells
Cells were grown to ~50% confluency before RNA polymerase activity was blocked with 10 µg/mL Actinomycin D (Sigma) in DMSO. Control cells were treated with DMSO alone. Transcriptional inhibition of N2A cells was conducted for 32 h with cells harvested at time zero (0 h) and after 30 min, 2, 4, 8, 16...
ORGANISM(S): Mus musculus 
2012-01-24 | E-MTAB-961 | biostudies-arrayexpress
UnknownDevelopment and validation of a harmonized memory score for multicenter Alzheimer's disease and related dementia research.
Not available
S-EPMC11998833 | biostudies-literature
TranscriptomicsMicroarray analysis of RNA stability in mouse Neuro-2A cells
Microarray analysis of RNA stability in mouse Neuro-2A cells
ORGANISM(S): Mus musculus 
2011-01-24 | E-MTAB-952 | biostudies-arrayexpress
Sort   by:  
 Page size