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MetabolomicsMetabolic profiling of Candida clinical isolates of different species and infection sources

Candida species are the most common cause of opportunistic fungal infections. Rapid identification and novel approaches for the characterization of these fungi are of great interest to improve the diagnosis and the knowledge about their pathogenic properties. This study aimed to characte...

2024-07-09 | MTBLS1978 | MetaboLights
MetabolomicsSequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID

The post-acute sequelae of COVID-19 (PASC), also known as long COVID, is often associated with debilitating symptoms and adverse multisystem consequences. We obtain plasma samples from 117 individuals during and 6 mth following their acute phase of infection to comprehensively profile and as...

2024-02-23 | MTBLS7337 | MetaboLights
ProteomicsProteomic analysis of SARS-CoV-2: A clinical landscape of COVID-19 proteome and host responses
A novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of COVID-19 and continues to be a global health challenge. To understand viral disease biology, we have carried out proteo-genomic analysis using next generation sequencing (NGS) and mass-spectrometry on naso...
ORGANISM(S): Homo sapiens (Human) 
2021-06-28 | PXD021896 | Pride
Sars-cov-2 Covid-19 proteins Clinical swabs Lc-ms/ms analysis Proteome/host response 
GenomicsClinical Nasopharyngeal Swabs and Inactivated SARS-CoV-2 Virions
Clinical Nasopharyngeal Swabs and Inactivated SARS-CoV-2 Virions Raw sequence reads
PRJNA766077 | ENA
MetabolomicsDirect on-swab metabolic profiling of vaginal microbiome:host interactions during pregnancy and preterm birth

The pregnancy vaginal microbiome contributes to risk of preterm birth, the primary cause of death in children under 5 years of age. Here we describe direct on-swab metabolic profiling by Desorption Electrospray Ionization Mass Spectrometry (DESI-MS) for sample preparation-free characterisation of...

2021-09-23 | MTBLS717 | MetaboLights
ProteomicsDetection of SARS-CoV-2 in nasal swabs using MALDI-MS
Detection of SARS-CoV-2 using RT-PCR and other advanced methods can achieve high accuracy. However, their application is limited in countries that lack sufficient resources to handle large-scale testing during the COVID-19 pandemic. Here, we describe a method to detect SARS-CoV-2 in nasal swabs usin...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000086175 | MassIVE
TranscriptomicsTranscriptomic analysis of acute and carrier GAS samples from oropharyngeal throat swabs.
The carrier state of Streptococcus pyogenes (Group A Strep, GAS), is defined by the presence of the organism without symptoms or an immune response. Carriage poses challenges for clinical management and contributes to transmission in the community. Comprehensive genomic and transcriptomic analyses o...
ORGANISM(S): Streptococcus pyogenes 
2026-08-12 | GSE309825 | GEO
ProteomicsDetection of SARS-CoV-2 in nasal swabs using MALDI-MS
Detection of SARS-CoV-2 using RT–PCR and other advanced methods can achieve high accuracy. However, their application is limited in countries that lack sufficient resources to handle large-scale testing during the COVID-19 pandemic. Here, we describe a method to detect SARS-CoV-2 in nasal swabs usin...
ORGANISM(S): Homo sapiens (Human) 
2020-09-11 | PXD021388 | Pride
Sars-cov-2 Human Maldi-ms Covid-19 
TranscriptomicsInteractome analysis of longitudinal pharyngeal infection of cynomolgus macaques by group A Streptococcus
Relatively little is understood about the dynamics of global host–pathogen transcriptome changes that occur during bacterial infection of mucosal surfaces. To test the hypothesis that group A Streptococcus (GAS) infection of the oropharynx provokes a host transcriptome response, we performed genom...
ORGANISM(S): Macaca fascicularis 
2010-03-18 | E-GEOD-20262 | biostudies-arrayexpress
ProteomicsLC-MS/MS proteomic analysis of pharyngeal swabs and plasma from MHV-infected and uninfected mice
Recent developments have broadened our perception of SARS-CoV-2, indicating its capability to affect the body systemically beyond its initial recognition as a mere respiratory pathogen. However, the pathways of its widespread are not well-understood. Employing a dual-modality approach, we integrated...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 Mus musculus (Mouse) 
2024-12-11 | PXD054355 | Pride
Pharyngeal swabs Mus musculus Mhv Plasma Lc-m/ms 
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