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ProteomicsLC-MS/MS proteomic analysis of pharyngeal swabs and plasma from MHV-infected and uninfected mice
Recent developments have broadened our perception of SARS-CoV-2, indicating its capability to affect the body systemically beyond its initial recognition as a mere respiratory pathogen. However, the pathways of its widespread are not well-understood. Employing a dual-modality approach, we integrated...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 Mus musculus (Mouse) 
2024-12-11 | PXD054355 | Pride
Pharyngeal swabs Mus musculus Mhv Plasma Lc-m/ms 
TranscriptomicsIdentification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68
Murine gammaherpesvirus 68 (MHV-68) is closely related to Epstein-Barr virus (EBV) and KaposiM-bM-^@M-^Ys sarcoma-associated herpesvirus (KSHV) and provides a small animal model to study the pathogenesis of gammaherpesvirus (M-NM-3HV) infections. To completely explore the potential of the MHV-68 sys...
ORGANISM(S): Mus musculus 
2010-07-15 | E-GEOD-22938 | biostudies-arrayexpress
ProteomicsLC-MSMS of Mice BMDC infected by MHV-A59
We conducted a comprehensive analysis of the proteome of mouse bone marrow dendritic cells (BMDCs) infected with MHV-A59. We characterized the global gene changes at the protein levels following viral infection, identifying ten genes involved in various anti-MHV biological processes.
ORGANISM(S): Mus musculus (Mouse) 
2025-06-06 | PXD061826 | Pride
Lc-msms Mhv Bmdc Mice 
TranscriptomicsRibosome profiling of mouse hepatitis virus (MHV)-infected and uninfected 17Cl1 cells
Ribosome profiling (RiboSeq) analysis of murine 17 clone 1 (17Cl-1) cells with and without MHV infection. We sought to assess the impact of differing library preparation methods by using three separate approaches: flash freezing, 1X cycloheximide pretreatment, and 100X cycloheximide pretreatment.
ORGANISM(S): Mus musculus 
2021-11-09 | E-MTAB-6278 | biostudies-arrayexpress
TranscriptomicsRNASeq of murine 17Cl-1 cells infected at MOI 10 with MHV-A59, compared to mock-infected controls, harvested at 5 and 8 hpi.
Murine 17Cl-1 cells were infected with the model Betacoronavirus mouse hepatitis virus (MHV) strain A59 to observe changes in the host transcriptome in infected cells compared to mock-infected cells. Samples were harvested at 5 and 8 hpi by flash-freezing, without cycloheximide pre-treatment. Riboso...
ORGANISM(S): Mus musculus 
2021-05-18 | E-MTAB-8651 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse brain tissue from three strains infected with mouse hepatitis virus (MHV) for 2 or 5 days
In this study we explored the antiviral gene expression induced in the CNS of MHV-infected mice, by performing whole-genome expression profiling. Three different mouse strains (BALB/c, 129SvEv and 129SvEv IFNAR-/- mice), differing in their susceptibility to infection with MHV, were used.
ORGANISM(S): Mus musculus 
2009-10-01 | E-MEXP-2081 | biostudies-arrayexpress
GenomicsBulk RNA-seq of MHV-A59 infection in primary murine macrophages
Bulk RNA-seq of MHV-A59 infection in primary murine macrophages
PRJNA770889 | ENA
TranscriptomicsRiboSeq of murine 17Cl-1 cells infected at MOI 10 with MHV-A59, compared to mock-infected controls, harvested at 5 and 8 hpi, plus a control tunicamycin-treated sample.
Murine 17Cl-1 cells were infected with the model Betacoronavirus mouse hepatitis virus (MHV) strain A59 and subjected to ribosome profiling to observe changes in the host translatome in infected cells compared to mock-infected cells. Samples were harvested at 5 and 8 hpi by flash-freezing, without c...
ORGANISM(S): Mus musculus 
2021-05-18 | E-MTAB-8650 | biostudies-arrayexpress
UnknownSolution structure of mouse hepatitis virus (MHV) nsp3a and determinants of the interaction with MHV nucleocapsid (N) protein.
Not available
S-EPMC3592139 | biostudies-literature
TranscriptomicsTranscription profiling of mouse fibroblasts infected with murine hepatitis virus using two array platforms to compare the potential for interference from viral RNA
Infection of cells with murine hepatitis virus strain A59 (MHV-A59) results in massive amounts of viral RNA within infected cells. When applying transcriptional profiling by means of microarray analysis, this could potentially cause problems since high amounts of viral RNA could in theory interfere ...
ORGANISM(S): Mus musculus 
2008-05-21 | E-MEXP-1373 | biostudies-arrayexpress
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