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Head and neck cancer (HNC) is a heterogeneous malignant disease with distinct global distribution. Metabolic adaptations of HNC are significantly gaining clinical interests nowadays. Here, we investigated effects of HNC on differential expression of volatile metabolites in human saliva. We applied h...
2019-06-03 | MTBLS760 | MetaboLights
Repetitive mild closed head injury (rmCHI) is a common type of traumatic brain injury and its incidence is increasing, not least due to an increase in the number of sports-related injuries. The underlying neuroimmune mechanisms secondary to trauma that link rmCHI to cognitive decline are not well...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-01 | PXD053772 | Pride
Closed Head Injury Inulin Mouse Stool Samples Raw sequence reads
Mouse model of closed head injury (rCHI) was assessed for the effect of single hit vs. repetitive hits (3 hits) on the behavioral, biochemical and neuroproteomics changes at the acute (3 days) and sub chronic (7 days) time points in the cortex and hippocampus brain regions. This study will assess th...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-23 | PXD011418 | Pride
Bulk RNA-seq of mouse brain following closed head injury: role of IL-1R1 signaling
An experiment was performed to investigate the perservation of gene expression upon metastasis of primary head and neck squamous cell carcinomas to the cervical lymph node.
ORGANISM(S): Homo sapiens 
Bulk RNA-seq was performed on brain tissue from mice following closed head injury (CHI) or sham surgery at 9h, 24h, and 72h post-injury. Four genotypes were studied: C57BL/6J wild-type, IL-1R1 global knockout (gKO), IL-1R1 endothelial restore (eRestore), and IL-1R1 neuronal restore (nRestore) to dis...
ORGANISM(S): Mus musculus 
2026-07-29 | GSE326452 | GEO
Repetitive mild closed head injury in adolescent mice is associated with impaired proteostasis, neuroinflammation, and tauopathy
Oral immunization of trout against infectious pancreatic necrosis virus (IPNV) have been recently reported by using a DNA vector coding the viral capsid VP2 gene encapsulated in alginate microspheres. We report here an study of the transcripts in head kidney and pyloric ceca 7 days after oral vaccin...
ORGANISM(S): Oncorhynchus mykiss 
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