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TranscriptomicsTranscription profiling by array of adipose samples from LDLR-/- mice to study response to anti-diabetic drug and dietary lifestyle interventions
Lean male mice were fed a high fat diet (HFD, lard 24% w/w) for 16 weeks. At 9 weeks, when all hallmarks of prediabetes were established, groups of mice were treated with drug (rosiglitazone, pioglitazone, T0901317, or salicylate) for another 7 weeks together with the high fat diet. An additional gr...
ORGANISM(S): Mus musculus 
2014-05-14 | E-GEOD-57659 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of hepatic response to anti-diabetic drug and dietary lifestyle interventions in LDLR-/- mice
Lean male mice were fed a high fat diet (HFD, lard 24% w/w) for 16 weeks. At 9 weeks, when all hallmarks of prediabetes were established, groups of mice were treated with drug (metformin, glibenclamide, sitagliptin, rosiglitazone, pioglitazone, fenofibrate, T0901317, atorvastatin, salicylate or rofe...
ORGANISM(S): Mus musculus 
2013-04-18 | E-MTAB-1063 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of mouse peripheral blood mononuclear cells from ApoE3*Leiden mice on a high-fat diet
The aim of experiment was to investigate gene expression changes over time in liver of ApoE3*Leiden mice on a high-fat diet. Transformed file with remapped and annotated probesets into Entrez gene-ids using the custom MBNI CDF-file (http://brainarray.mbni.med.umich.edu/Brainarray/Database/CustomCDF/...
ORGANISM(S): Mus musculus 
2011-04-01 | E-TABM-959 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of peripheral blood mononuclear cells and adipose tissue from overweight men fed an anit-inflammatory dietary mix
It was hypothesized that specific dietary components are able to reduce low grade inflammation, as well as metabolic stress and oxidative stress in overweight men
ORGANISM(S): Homo sapiens 
2010-03-25 | E-TABM-871 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of liver, skeletal muscle and white adipose tissue from ApoE3L mice
Our aim was to investigate gene expression changes over time in liver of ApOE3*Leiden mice on a high-fat diet. Probesets were remapped and annotated into Entrez gene-ids using the custom MBNI CDF-file, version 9.0.1 - the GCRMA data generated
ORGANISM(S): Mus musculus 
2010-07-28 | E-TABM-1039 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of ApoE3Leiden mice exposed to varying doses of cholesterol to examine the effects of dietary cholesterol on liver homeostasis in the context of early atherosclerotic lesion development
A dose-response study of the effects of dietary cholesterol on liver homeostasis in the context of early atherosclerotic lesion development using ApoE3Leiden mice
ORGANISM(S): Mus musculus 
2007-10-13 | E-TABM-253 | biostudies-arrayexpress
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