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Adaptive laboratory evolution has proven highly effective for obtaining microorganisms with enhanced capabilities. Yet, this method is inherently restricted to the traits that are positively linked to cell fitness, such as nutrient utilization. Here, we introduce coevolution of obligatory mutuali...

2021-07-02 | MTBLS2217 | MetaboLights

It was further confirmed the stimulatory effect of M. loti-derived eCA on microalgae, highlighting key carbon metabolic pathways, including the Calvin cycle, TCA cycle and antioxidant defense response.

2025-01-20 | MTBLS11422 | MetaboLights
The present study aims to explore chemostat-based transcriptome analysis of mixed cultures by investigating interactions between the yeast S. cerevisiae and the lactic acid bacterium Lb. bulgaricus . S. cerevisiae and Lb. bulgaricus are both frequently encountered in kefir, a fermented dairy product...
ORGANISM(S): Saccharomyces cerevisiae 
The study recapitulates, through in vitro micropatterned co-cultures, interactions between HIV-infected T-lymphocytes and intestinal epithelial cells in order to investigate the mechanisms underlying the disruption of normal epithelial cell and barrier function during HIV infection. The co-culture m...
ORGANISM(S): Homo sapiens 
Co-cultures of enteric neurons and T cells
Glioblastoma (GBM) remains the most malignant primary brain tumor, with a median survival rarely exceeding 2 years. Tumor heterogeneity and an immunosuppressive microenvironment are key factors contributing to the poor response rates of current therapeutic approaches. GBM-associated macrophages (GAM...
Non-targeted metabolomics analysis of cell and medium extract obtained by bacterial co-cultures.
ORGANISM(S): Environmental Samples <bacillariophyta> (ncbitaxon:33858) 
2023-03-09 | MSV000091452 | MassIVE
Expression data from prostate cancer and osteoblast co-cultures
Although desert dust is known to cause increased respiratory morbidity and mortality, the underlying biological pathways remain unclear. We used RNA-seq on an advanced human alveolar in vitro model to find yet unidentified genes dysregulated by Saharan dust exposure. For comparison, DQ12 quartz dust...
ORGANISM(S): Homo sapiens 
Tissue-resident memory T cells- iPSC-cardiomyocyte co-cultures
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