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TranscriptomicsCodY of Streptococcus pneumoniae: link between nutritional gene regulation and virulence
CodY is a nutritional regulator mainly involved in amino acid metabolism. It has been extensively studied in Bacillis subtilis and Lactococcus lactis. We investigated the role of CodY in gene regulation and virulence of the human pathogen Streptococcus pneumoniae. We constructed a codY-mutant and ex...
ORGANISM(S): Streptococcus pneumoniae TIGR4 
2010-05-25 | E-GEOD-7350 | biostudies-arrayexpress
TranscriptomicsMultiple roles for CodY in the type strain Bacillus cereus ATCC 14579
Comparison of the B cereus codY deletion mutant with wild type strain (ATCC 14579) One condition design comparision of mutant vs wild type including a dye swap, 4 biological replicate
ORGANISM(S): Bacillus cereus ATCC 14579 
2012-07-04 | E-GEOD-31017 | biostudies-arrayexpress
MetabolomicsInterplay of CodY and CcpA in regulating central metabolism and biofilm formation in S. aureus
Not available
ORGANISM(S): Staphylococcus aureus 
ST002187 | MetabolomicsWorkbench
UnknownStructural analysis of Pneumocystis carinii and human DHFR complexes with NADPH and a series of five potent 6-[5'-(ω-carboxyalkoxy)benzyl]pyrido[2,3-d]pyrimidine derivatives.
Not available
S-EPMC3016015 | biostudies-literature
ProteomicsCodY regulates the activity of the virulence quorum sensor PlcR
In Gram-positive bacteria, cell-cell communication mainly relies on cytoplasmic sensors of the RNPP family. Activity of these regulators depends on their binding to secreted signaling peptides that are imported into the cell. These quorum sensing regulators control important biological functions in ...
ORGANISM(S): Bacillus thuringiensis Bt407 
2015-12-17 | PXD003311 | Pride
Opp Bacillus Cody Mass spectrometry Plcr Signaling peptide Quorum-sensing Virulence regulon Shot gun Regulation 
UnknownNanI Sialidase, CcpA, and CodY Work Together To Regulate Epsilon Toxin Production by Clostridium perfringens Type D Strain CN3718.
Not available
S-EPMC4573732 | biostudies-literature
TranscriptomicsTranscription profiling of B anthracis wild type and codY mutant 7CodYS
B. anthracis 7702 and the codY mutant 7CodYS were grown in R-medium (Ristroph, J.D. & Ivins, B.E. (1983). Elaboration of Bacillus anthracis antigens in a new, defined culture medium. Infect. Immun. 39:483-486) with 0.6% sodium bicarbonate until A600 = 0.2 or 1.0. The transcriptome of both strains wa...
ORGANISM(S): Bacillus anthracis 
2008-11-15 | E-MEXP-1706 | biostudies-arrayexpress
TranscriptomicsInvestigating the effect of CodY mutation on the gene expression in Streptococcus suis serotype 2 SC19 strain.
To investigate the effect of CodY mutation on the gene expression in Streptococcus suis serotype 2 SC19 strain, we have employed whole genome microarray expression profiling as a discovery platform to identify genes regulated by CodY mutation. DNA microarray analysis was performed using an Agilent c...
ORGANISM(S): Streptococcus suis 
2015-04-21 | E-GEOD-68068 | biostudies-arrayexpress
UnknownPreferential selection of isomer binding from chiral mixtures: alternate binding modes observed for the E and Z isomers of a series of 5-substituted 2,4-diaminofuro[2,3-d]pyrimidines as ternary complexes with NADPH and human dihydrofolate reductase.
Not available
S-EPMC2995722 | biostudies-literature
UnknownCodY activates transcription of a small RNA in Bacillus subtilis.
Not available
S-EPMC2725614 | biostudies-literature
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