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TranscriptomicsCulture induced changes in Blood-Brain Barrier transcriptome: implications for amino acid transporters in vivo
Tight homeostatic control of brain amino acids (AA) depends on transport via solute family carrier proteins expressed by the Blood-Brain Barrier (BBB) microvascular endothelial cells (BMEC). To characterize the mouse BMEC transcriptome and probe culture-induced changes microarray analyses of PECAM-1...
ORGANISM(S): Mus musculus 
2010-05-18 | E-GEOD-14375 | biostudies-arrayexpress
TranscriptomicsTubulointerstitial transcriptome from ERCB subjects with chronic kidney disease and living donor biopsies.
Tubulointerstitial transcriptome from ERCB subjects with chronic kidney disease and living donor biopsies. Samples included in this analysis have been previously analyzed using older CDF definitions and are included under previous GEO submissions - GSE47184 (chronic kidney disease samples), and GSE3...
ORGANISM(S): Homo sapiens 
2018-01-24 | E-GEOD-104954 | biostudies-arrayexpress
TranscriptomicsGlomerular Transcriptome from European Renal cDNA Bank subjects and living donors
Glomerular Transcriptome from European Renal cDNA Bank subjects and living donors. Samples included in this analysis have been previously analyzed using older CDF definitions and are included under previous GEO submissions - GSE47183 (chronic kidney disease samples), and GSE32591 (IgA nephropathy sa...
ORGANISM(S): Homo sapiens 
2018-01-24 | E-GEOD-104948 | biostudies-arrayexpress
TranscriptomicsTissue Transcriptome Driven Identification of Epidermal Growth Factor as a Chronic Kidney Disease Biomarker
We identified EGF as the top candidates predicting kidney function through an intrarenal transcriptome-driven approach, and demonstrated it is an independent risk predictor of CKD progression and can significantly improve prediction of renal outcome by established clinical parameters in diverse popu...
ORGANISM(S): Homo sapiens 
2015-12-14 | E-GEOD-69438 | biostudies-arrayexpress
UnknownDaratumumab monotherapy for patients with intermediate-risk or high-risk smoldering multiple myeloma: a randomized, open-label, multicenter, phase 2 study (CENTAURUS).
Not available
S-EPMC7326703 | biostudies-literature
TranscriptomicsExpression data from human with IgA nephropathy (IgAN)
This SuperSeries is composed of the following subset Series: GSE35487: Expression data from human with IgA nephropathy (IgAN) [HG-U133A] GSE35488: Expression data from human with IgA nephropathy (IgAN) [HG-U133A_ENTREZG_10] Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-02-02 | E-GEOD-35489 | biostudies-arrayexpress
TranscriptomicsExpression data from human with IgA nephropathy (IgAN) [HG-U133A]
Proteinuria is the most important predictor of outcome in glomerulonephritis and experimental data suggest that the tubular cell response to proteinuria is an important determinant of progressive fibrosis in the kidney. However, it is unclear whether proteinuria is a marker of disease severity or h...
ORGANISM(S): Homo sapiens 
2012-02-02 | E-GEOD-35487 | biostudies-arrayexpress
TranscriptomicsExpression data from human with IgA nephropathy (IgAN) [HG-U133A_ENTREZG_10]
Proteinuria is the most important predictor of outcome in glomerulonephritis and experimental data suggest that the tubular cell response to proteinuria is an important determinant of progressive fibrosis in the kidney. However, it is unclear whether proteinuria is a marker of disease severity or h...
ORGANISM(S): Homo sapiens 
2012-02-02 | E-GEOD-35488 | biostudies-arrayexpress
TranscriptomicsExpression data from human with lupus nephritis (LN)
Nephritis (LN) is a serious manifestation of SLE. Therapeutic studies in mouse LN models do not always predict outcomes of human therapeutic trials, raising concerns about the human relevance of these models. In this study we used an unbiased transcriptional network approach to define similarities a...
ORGANISM(S): Homo sapiens 
2012-06-27 | E-GEOD-32591 | biostudies-arrayexpress
TranscriptomicsIn silico nano-dissection: defining cell type specificity at transcriptional level in human disease (tubulointerstitium)
To identify genes with cell-lineage-specific expression not accessible by experimental micro-dissection, we developed a genome-scale iterative method, in-silico nano-dissection, which leverages high-throughput functional-genomics data from tissue homogenates using a machine-learning framework. This ...
ORGANISM(S): Homo sapiens 
2013-08-06 | E-GEOD-47184 | biostudies-arrayexpress
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