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UnknownAdult-onset liver disease and hepatocellular carcinoma in S-adenosylhomocysteine hydrolase deficiency.
Not available
S-EPMC4733618 | biostudies-literature
UnknownSirt6 prevents the age-related decline of H<sub>2</sub>S through the control of one-carbon metabolism.
Not available
S-EPMC12646208 | biostudies-literature
UnknownEfficacy and safety of metabolic interventions for the treatment of severe COVID-19: in vitro, observational, and non-randomized open-label interventional study.
Not available
S-EPMC9937660 | biostudies-literature
ProteomicsChemical genetics and proteome-wide site mapping reveal cysteine MARylation by PARP-7 on immune-relevant protein targets
Poly (ADP-ribose) polymerase 7 (PARP-7) has emerged as a critically important member of a large enzyme family that catalyze ADP-ribosylation in mammalian cells. PARP-7 is a critical regulator of the innate immune response. What remains unclear is the mechanism by which PARP-7 regulates this process,...
ORGANISM(S): Homo sapiens (Human) 
2021-07-21 | PXD020323 | Pride
Chemical genetics Marylation Parp-7 Protein-protein interactions Enzymatic targets 
TranscriptomicsSmall RNA sequencing of melanoma samples to deduce microRNA expression profiles
We report results on microRNA profiles revealing the distribution of "isomirs" of microRNA in a cancerous state. Deep sequencing was conducted at Stanford University and data analysis was conducted at the University of Connecticut Health Center. Small RNA profiling to deduce differential m...
ORGANISM(S): Homo sapiens 
2012-03-13 | E-GEOD-36236 | biostudies-arrayexpress
ProteomicsThe mitochondrial chaperone HSPD1 folds MTHFD2 independently of its co-chaperone HSPE1
Acquiring new cellular states entails metabolic reprogramming driven by adjustments to the expression of metabolic enzymes in the cytosol and mitochondria. Most mitochondrial proteins are synthesized in the cytosol and imported into the mitochondria in a linear form, after which they are folded by a...
ORGANISM(S): Homo sapiens (Human) 
2026-10-05 | PXD066753 | Pride
Metabolism One carbon Mthfd2 Hspd1 Protein folding Hspe1 
UnknownComparing single-best-answer and very-short-answer questions for the assessment of applied medical knowledge in 20 UK medical schools: Cross-sectional study.
Not available
S-EPMC6773319 | biostudies-literature
UnknownEffectiveness of an insurance enrollment support tool on insurance rates and cancer prevention in community health centers: a quasi-experimental study.
Not available
S-EPMC8557589 | biostudies-literature
TranscriptomicsZNF750 in late keratinocyte differentiation
Disrupted skin barrier due to altered keratinocyte differentiation is common in pathologic conditions such as atopic dermatitis, ichthyosis and psoriasis. However, the molecular cascades governing keratinocyte terminal differentiation are still poorly understood. We have previously demostrated that ...
ORGANISM(S): Homo sapiens 
2012-09-24 | E-GEOD-38039 | biostudies-arrayexpress
UnknownGermline EPHB2 receptor variants in familial colorectal cancer.
Not available
S-EPMC2483346 | biostudies-literature
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