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Dupuytren’s disease is a fibroproliferative disorder of the palmer fascia characterized by flexion contractures in the hand. Dupuytren’s can be treated surgically but disease recurrence rates are high, potentially due to a continual production of matrisomal proteins. Metabolic labelling and proteomi...
ORGANISM(S): Homo sapiens (Human) 
2026-03-16 | PXD069194 | Pride
Gene expression profiles were assessed in the hippocampus (HC), entorhinal cortex (EC), superior frontal gyrus (SG), and postcentral gyrus (PCG) across the lifespan of 63 cognitively intact individuals from 20-99 years old. New perspectives on the global gene changes that are associated with brain ...
ORGANISM(S): Homo sapiens 
Four unrelated families with the same unbalanced translocation der(4)t(4;11)(p16.2;p15.4) were identified. Both of the breakpoint regions in 4p16.2 and 11p15.4 were narrowed to large ~359-kb and ~215-kb low-copy repeat (LCR) clusters, respectively, by aCGH and SNP array analyses. DNA sequencing ena...
ORGANISM(S): Homo sapiens 
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