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TranscriptomicsEffects of physiological and synthetic IAP antagonism on c-IAP dependent signaling
Cellular inhibitor of apoptosis proteins 1 and 2 (c-IAP1/2) play central roles in signal transduction mediated by numerous receptors that participate in inflammatory and immune responses. In certain pathways, such as activation of NF-kB, their degradation is a major regulatory event and is physiolog...
ORGANISM(S): Homo sapiens 
2015-02-09 | E-GEOD-64927 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of male Fech mutant BALB/c mouse livers vs male control BALB/c livers
Comparison of gene expression in livers of male Fech mutant BALB/c mouse with livers of male control BALB/c
ORGANISM(S): Mus musculus 
2005-10-14 | E-MEXP-189 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of 4 week old BALB/c_Fech m1Pas mice (Fech) vs with 4 week old control BALB/c mice
Comparison of liver gene expression of 4 week old BALB/c_Fech m1Pas mice(Fech mice for short) with 4 week old control BALB/c mice.
ORGANISM(S): Mus musculus 
2005-10-21 | E-MEXP-194 | biostudies-arrayexpress
TranscriptomicsPRPF8 CLIP seq for iPSC, kidney organoid, retinal organoid, and retinal epithelium derived from c.6926A>C RPE with Retinitis Pigmentosa patients and CRISPR/Cas9 corrected
Retinitis Pigmentosa is a group of inherited eye disorders characterized by progressive degeneration of photoreceptor cells in the retina, leading to vision loss and eventual blindness. One of the known genetic mutations associated with RP is the c.6926A>C mutation in the RPE (retinal pigment epithe...
ORGANISM(S): Homo sapiens 
2024-03-13 | E-MTAB-13171 | biostudies-arrayexpress
TranscriptomicsUsing GRO-seq experiments to determine the mechanism of C. elegans dosage compensation's control of transcription
Dosage Compensation is required to correct for uneven gene dose between the sexes. We utilized global run-on sequencing (GRO-seq) to examine how Caenorhabditis elegans dosage compensation reduces transcription of X-linked genes. To facilitate these experiments, we required accurate 5M-bM-^@M-^Y-ends...
ORGANISM(S): Caenorhabditis elegans 
2013-06-18 | E-GEOD-43084 | biostudies-arrayexpress
GenomicsBinding of the C. elegans dosage compensation complex protein DPY-27
Dosage Compensation is required to correct for uneven gene dose between the sexes. We utilized global run-on sequencing (GRO-seq) to examine how Caenorhabditis elegans dosage compensation reduces transcription of X-linked genes. To facilitate these experiments, we required accurate 5M-bM-^@M-^Y-ends...
ORGANISM(S): Caenorhabditis elegans 
2013-06-18 | E-GEOD-43086 | biostudies-arrayexpress
TranscriptomicsmRNA-seq of L1 larvae recovering from arrest
We used RNA-seq to sequence the transcriptome of worms arrested in the first larval stage after hatching without food and starved for 12 hours, then a timecourse of animals recovering from arrest after feeding. We collected samples after 12 hours of starvation and 1, 3 and 6 hours after feeding. Fou...
ORGANISM(S): Caenorhabditis elegans 
2012-04-25 | E-GEOD-33023 | biostudies-arrayexpress
UnknownPaltolides A--C, anabaenopeptin-type peptides from the palau sponge Theonella swinhoei.
Not available
S-EPMC2885440 | biostudies-literature
Transcriptomics16S rDNA sequencing of BALB/c and C57BL/7 mouse gut microbiomes
Age-dependent changes of the gut-associated microbiome have been linked to increased frailty and systemic inflammation. This study found that age-associated changes of the gut microbiome of BALB/c and C57BL/6 mice could be reverted by co-housing of aged (22 months old) and adult (3 months old) mice ...
ORGANISM(S): Mus musculus 
2019-05-08 | E-MTAB-7750 | biostudies-arrayexpress
TranscriptomicsDevelopment of GRO-cap (GRO-seq followed by 5'-cap enrichment) to map transcription start sites in C. elegans
Dosage Compensation is required to correct for uneven gene dose between the sexes. We utilized global run-on sequencing (GRO-seq) to examine how Caenorhabditis elegans dosage compensation reduces transcription of X-linked genes. To facilitate these experiments, we required accurate 5M-bM-^@M-^Y-ends...
ORGANISM(S): Caenorhabditis elegans 
2013-06-18 | E-GEOD-43085 | biostudies-arrayexpress
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