Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of rat mixed-tissue RNA samples using different labeling protocols
At one site (#10), three different batches of MTRRM (see E-TABM-16), were labeled with two different kits (Enzo and Affymetrix) and hybridized to two different Affymetrix Arrays (RAE230A and RAE230_2).
ORGANISM(S): Rattus norvegicus 
2008-04-16 | E-MEXP-1563 | biostudies-arrayexpress
TranscriptomicsmiRNA expression profile in platelets after ex vivo activation
We performed microRNA sequencing (miRNA-seq) according to Illumina sequencing protocols. Platelet-rich plasma (PRP) has been obtained by centrifuging whole blood at 160 x g for 15 min at room temperature. Platelets have been activated with 3 different physiologic agonists, namely ADP (20uM), collage...
ORGANISM(S): Homo sapiens 
2015-04-27 | E-MTAB-2078 | biostudies-arrayexpress
TranscriptomicsEvaluating microRNA profiles reveals discriminative responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytes [Exiqon]
The study investigated differential miRNA changes in primary mouse hepatocyte following 24 and 48 hours of exposure to aflatoxin B1, cisplatin, benzo(a)pyrene, 2,3,7,8-tetrachloordibenzo-p-dioxine, cyclosporin A or Wy-14,643 or their responsive solvent. Three (four for Wy-14,643) biological replica...
ORGANISM(S): Mus musculus 
2015-05-18 | E-GEOD-57082 | biostudies-arrayexpress
no omics definedTranscription profiling of fresh and frozen rat liver RNA samples to explore how RNA quality affects microarray results
To systemically explore how RNA quality affects microarray assay results, a set of rat liver RNA samples with a progressive change in RNA quality was generated either by thawing frozen tissue or by ex vivo incubation of fresh tissue.
ORGANISM(S): Rattus norvegicus 
2007-09-01 | E-MEXP-1069 | biostudies-arrayexpress
TranscriptomicsEvaluating microRNA profiles reveals discriminative responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytes [Affymetrix]
The study investigated differential gene expression in primary mouse hepatocyte mRNA following 24 and 48 hours of exposure to aflatoxin B1, cisplatin, benzo(a)pyrene, 2,3,7,8-tetrachloordibenzo-p-dioxine, cyclosporin A or Wy-14,643 or their responsive solvent. Three (four for Wy-14,643) biological ...
ORGANISM(S): Mus musculus 
2015-05-18 | E-GEOD-57129 | biostudies-arrayexpress
UnknownCulturing Ancient Bacteria Carrying Resistance Genes from Permafrost and Comparative Genomics with Modern Isolates.
Not available
S-EPMC7600834 | biostudies-literature
ProteomicsPeptidomics of pancreas in wild type and neuronatin deficien mice
Pancreata of wild type and a neuronatin deficient mouse strain were homogenised and the peptidome characterised. Particular attention was paid to the processing of insulin, to assess if neuronatin deficiency causes changes in the processing efficiency of insulin and other bioactive peptides produced...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-03 | PXD024161 | Pride
Neuronatin Prohormone processing Peptidomics Pancreas Insulin 
TranscriptomicsTranscriptome profiling of deciduas from pre-eclamptic and normotensive pregnancies
Genome-wide analysis of decidual transcriptome in pre-eclampsia compared with normotensive controls to find differentially expressed genes/pathways. Preeclampsia (PE) is a common and serious pregnancy hypertensive disorder with a strong genetic component. The study aims were to use genome-wide analy...
ORGANISM(S): Homo sapiens 
2015-08-05 | E-GEOD-60438 | biostudies-arrayexpress
TranscriptomicsFunctionally-relevant splicing of resident pre-mRNAs in anucleate platelets upon activation by physiological stimuli
Platelet activation is the key event triggering thrombus formation in physiological and pathological conditions, such as acute coronary syndromes. Current therapies using antiaggregants still fail to prevent thrombotic coronary events in a significant number of patients, indicating that the mechanis...
ORGANISM(S): Homo sapiens 
2018-01-15 | E-MTAB-6148 | biostudies-arrayexpress
UnknownEfficacy and safety of cytoreductive therapies in patients with essential thrombocythaemia aged >80 years: an interim analysis of the EXELS study.
Not available
S-EPMC3586170 | biostudies-literature
Sort   by:  
 Page size