Sort   by:  
 Page size 
ProteomicsAP-SWATH analysis reveals a direct involvement of VCP/p97 in integrated stress response signalling through CReP/PPP1R15B degradation
The ubiquitin-directed AAA-ATPase VCP/p97 facilitates degradation of misfolded proteins in diverse cellular stress response pathways. Resolving the complexity of dynamic interactions with hosts of accessory proteins and substrates has therefore been a major challenge. Here, we used affinity-purifica...
ORGANISM(S): Homo sapiens (Human) 
2018-04-04 | PXD007876 | Pride
Integrated stress response Ap-swath P97 
TranscriptomicsChIP-chip from Kc cells with Su(H) antibodies after 30 minutes Notch activation
During hematopoiesis, Notch regulates both the emergence of stem and progenitor cells and the subsequent cell fate choices and differentiation. To investigate how Notch drives cells to differentiate we have used a genome-wide approach to identify direct Notch targets in Drosophila Kc cells. These da...
ORGANISM(S): Drosophila melanogaster 
2013-03-08 | E-GEOD-43132 | biostudies-arrayexpress
ProteomicsIn vivo and in vitro proteome analysis of HIV-1 infected, human CD4+ T cells
Host directed therapies against HIV-1 are thought to be critical for long term containment of the HIV-1 pandemic but remain elusive. Since HIV-1 infects and manipulates important effectors of both the innate and adaptive immune system, identifying modulations of the host cell systems in humans durin...
ORGANISM(S): Homo sapiens (Human) 
2017-02-28 | PXD005234 | Pride
Cd4 t cell Hiv Swath 
TranscriptomicsH. pylori infection blocks DNA damage induced apoptosis by T4SS-dependent upregulation of miR-155
The innate immune response against Helicobacter pylori is mainly controlled by pattern recognition receptors that lead to the up-regulation of pro-inflammatory cytokines. A new player in this field is the miR-155 being regulated by TLR ligands in monocytic derived cells influencing certain intracell...
ORGANISM(S): Mus musculus 
2012-04-02 | E-GEOD-29388 | biostudies-arrayexpress
UnknownRhodium-catalyzed oxidative cycloaddition of benzamides and alkynes via C-H/N-H activation.
Not available
S-EPMC2929375 | biostudies-literature
UnknownA case of treacher collins syndrome.
Not available
S-EPMC4001420 | biostudies-literature
UnknownCatalytic asymmetric allylic and homoallylic diamination of terminal olefins via formal C-H activation.
Not available
S-EPMC2776772 | biostudies-literature
UnknownDirect Benzylic C-H Etherification Enabled by Base-Promoted Halogen Transfer.
Not available
S-EPMC12186767 | biostudies-literature
UnknownExpanding chemical space by para-C-H arylation of arenes.
Not available
S-EPMC9270437 | biostudies-literature
TranscriptomicsMacrophages recognize the Helicobacter pylori type IV secretion system in the absence of TLR signaling
Helicobacter pylori conquered the world by colonizing the human stomach. There are two major groups of strains, one with and one without a cag pathogenicity island (cagPAI), which result in different clinical outcomes with increased severity in cagPAI+ H. pylori infections such as higher inflammatio...
ORGANISM(S): Mus musculus 
2015-09-01 | E-GEOD-56791 | biostudies-arrayexpress
Sort   by:  
 Page size