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ProteomicsPersonalized proteome profiles of healthy and tumor human colon organoids reveal both individual diversity and basic features of colorectal cancer.
We performed quantitative mass spectrometry based proteomic analysis and comparative transcriptomics analysis of 7 individual patient-derived human colorectal tumor and healthy organoids, the latter acquired from adjacent healthy tissue.
ORGANISM(S): Homo sapiens (Human) 
2017-01-16 | PXD004149 | Pride
Proteomics Organoids Colon cancer 
UnknownUNR/CSDE1 Expression Is Critical to Maintain Invasive Phenotype of Colorectal Cancer through Regulation of c-MYC and Epithelial-to-Mesenchymal Transition.
Not available
S-EPMC6517883 | biostudies-literature
ProteomicsRNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer
Wnt/b-catenin signaling is a primary pathway for stem cell maintenance during tissue renewal and a frequent target for mutations in cancer. Impaired Wnt receptor endocytosis due to loss of the ubiquitin ligase RNF43 gives rise to Wnt-hypersensitive tumors that are susceptible to anti-Wnt-based thera...
ORGANISM(S): Homo sapiens (Human) 
2020-08-14 | PXD020478 | Pride
Porcn inhibitors Cancer mutations Rnf 43 Human colon organoids Wnt signaling Lc-ms/ms 
UnknownOrganotypic culture as a research and preclinical model to study uterine leiomyomas.
Not available
S-EPMC7090073 | biostudies-literature
UnknownEarly Diagnosis of Atrial Fibrillation and Stroke Incidence in Primary Care: Translating Measurements into Actions-A Retrospective Cohort Study.
Not available
S-EPMC10135492 | biostudies-literature
UnknownMicroRNA-19b Plays a Key Role in 5-Fluorouracil Resistance and Predicts Tumor Progression in Locally Advanced Rectal Cancer Patients.
Not available
S-EPMC9604503 | biostudies-literature
UnknownDynamics of Ischemia/Reperfusion Injury Markers During Normothermic Liver Machine Perfusion.
Not available
S-EPMC11567704 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
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