Sort   by:  
 Page size 
ProteomicsUlcerative Colitis-Derived Colonoid Culture: 2 A multi-mineral-approach to improve barrier protein expression
Background. Recent studies demonstrated that Aquamin®, a calcium-, magnesium-, and multiple trace element-rich natural product, improves barrier structure and function in colonoids obtained from the tissue of healthy subjects. The goal of the present study was to determine if the colonic barrier co...
ORGANISM(S): Homo sapiens (Human) 
2020-12-17 | PXD020244 | Pride
Basement membrane Desmosome Calcium Colonoid Cell barrier 29 proteomics Ulcerative colitis 
TranscriptomicsWhole-exome sequencing (WES) to assess genomic concordance between an adenoma/adenocarcinoma colonoid culture 14-881 and the source patient tissue
A patient-derived epithelium-only colon rectal organoid, also referred to as a colonoid, was generated from an adenoma (associated with a resection surgery of an invasive moderately differentiated colorectal adenocarcinoma) as part of the development of an on-going organoid biobank at the Michigan M...
ORGANISM(S): Homo sapiens 
2020-12-22 | E-MTAB-9936 | biostudies-arrayexpress
UnknownUsing a human colonoid-derived monolayer to study bacteriophage translocation.
Not available
S-EPMC10962583 | biostudies-literature
GenomicsDNA Methylation Profiling of Human Colonoid Monolayers Under Repeated Submergence Injury
DNA Methylation Profiling of Human Colonoid Monolayers Under Repeated Submergence Injury
PRJNA740031 | ENA
GenomicsBiopsy-derived colonoid air-liquid interface monolayers reveal persistent mucosal defects in ulcerative colitis patients
Biopsy-derived colonoid air-liquid interface monolayers reveal persistent mucosal defects in ulcerative colitis patients
PRJNA1274514 | ENA
GenomicsWhole-exome sequencing (WES) to assess genomic concordance between an adenoma/adenocarcinoma colonoid culture 14-881 and the source patient tissue
Whole-exome sequencing (WES) to assess genomic concordance between an adenoma/adenocarcinoma colonoid culture 14-881 and the source patient tissue
PRJEB42180 | ENA
TranscriptomicsBiopsy-derived colonoid air-liquid interface monolayers reveal persistent mucosal defects in ulcerative colitis patients
Background: The Inflammatory Bowel Disease (IBD) ulcerative colitis (UC) is characterized by colonic mucosal inflammation and barrier dysfunction. We hypothesize that UC causes persistent defects in mucosal homeostasis, evident even in the absence of active inflammation, contributing to disease chro...
ORGANISM(S): Homo sapiens 
2026-01-29 | GSE299477 | GEO
UnknownCalcium-Induced Differentiation of Human Colon Adenomas in Colonoid Culture: Calcium Alone versus Calcium with Additional Trace Elements.
Not available
S-EPMC6030430 | biostudies-literature
Methylation profilingDNA Methylation Profiling of Human Colonoid Monolayers Under Repeated Submergence Injury
Acute damage to the intestinal epithelium can be repaired via de-differentiation of mature intestinal epithelial cells to a stem cell state, but there is a lack of knowledge on how these stem cells function after chronic injury, such as in inflammatory bowel disease (IBD). We developed a chronic inj...
ORGANISM(S): Homo sapiens 
2021-06-23 | GSE178700 | GEO
UnknownThe Air-Liquid Interface Reorganizes Membrane Lipids and Enhances the Recruitment of Slc26a3 to Lipid-Rich Domains in Human Colonoid Monolayers.
Not available
S-EPMC10179158 | biostudies-literature
Sort   by:  
 Page size