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Doxorubicin (DOX) is a widely used chemotherapeutic agent that can cause off-target gastrointestinal (GI) toxicity. This experiment profiles DOX-induced transcriptomic responses by RNA-seq in mouse colonoids (in vitro) across dose and time. Mouse colonoids were sampled at 24, 48 and 72 h after expos...
ORGANISM(S): Mus musculus 
Transcriptomics analysis of iron chelator deferoxamine treated human tumor colonoids.
Doxorubicin-exposed mouse colon tissue and mouse colonoids RNA-seq
Transcriptional response of human enteroids/colonoids on transwells to infection
RNA-Sequencing of epithelium and colonoids from patients with pediatric inflammatory bowel disease
The goal of this study was to evaluate the transcriptional response of human enteroids/colonoids on transwells to infections (bacterial and rotavirus). Enteroids/colonoids lines C103, C109, D103, D109, I103, I109, J2 and J11 were plated on transwells coated with Matrigel, differentiated, and inocula...
ORGANISM(S): Homo sapiens 
2021-10-01 | GSE183222 | GEO
Novel lentiviral constructs for the specification of rare and ectopic cell types in human colonoids
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