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ProteomicsComplementarity Determining Regions in SARS-CoV-2 hybrid immunity
Pre-vaccination SARS-CoV-2 infection can boost protection elicited by COVID-19 vaccination and post-vaccination breakthrough SARS-CoV-2 infection can boost existing immunity conferred by COVID-19 vaccination. Such ‘hybrid immunity’ is effective against SARS-CoV-2 variants. In order to understand ‘hy...
ORGANISM(S): Homo sapiens (Human) 
2023-02-08 | PXD038849 | Pride
Human Cdr Covid 19 
ProteomicsRole of Complementarity-Determining Regions 1 and 3 in Pathologic Amyloid Formation by Human Immunoglobulin κ1 Light Chains
Immunoglobulin light chain (LC) amyloidosis is a life-threatening disease whose understanding and treatment is complicated by vast numbers of patient-specific mutations. To address molecular origins of the disease, we explored 14 patient-derived and engineered proteins related to κ1-family germline ...
ORGANISM(S): Homo sapiens (Human) 
2023-05-23 | PXD039682 | Pride
Light chain amyloidosis  misfolded states  protein stability  protein dynamics  hdx ms  hydrogen deuterium exchange mass spectrometry 
UnknownCerebrospinal-fluid-derived immunoglobulin G of different multiple sclerosis patients shares mutated sequences in complementarity determining regions.
Not available
S-EPMC3861734 | biostudies-literature
UnknownComplementarity determining regions in SARS-CoV-2 hybrid immunity.
Not available
S-EPMC9990870 | biostudies-literature
UnknownAbFlex: designing antibody complementarity determining regions with flexible CDR definition.
Not available
S-EPMC10965422 | biostudies-literature
UnknownHuman antibody polyreactivity is governed primarily by the heavy-chain complementarity-determining regions.
Not available
S-EPMC11564698 | biostudies-literature
UnknownA complete, multi-level conformational clustering of antibody complementarity-determining regions.
Not available
S-EPMC4103072 | biostudies-literature
UnknownThe complementarity-determining region sequences in IgY antivenom hypervariable regions.
Not available
S-EPMC5512210 | biostudies-literature
UnknownOxidation in the complementarity-determining regions differentially influences the properties of therapeutic antibodies.
Not available
S-EPMC5098445 | biostudies-literature
UnknownArginine mutations in antibody complementarity-determining regions display context-dependent affinity/specificity trade-offs.
Not available
S-EPMC5633126 | biostudies-literature
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