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Osteoarthritis (OA) is characterised by loss of articular cartilage, synovial membrane dysfunction and subchondral sclerosis. Few studies have used a global approach to stratify equine synovial fluid (SF) molecular profiles according to OA severity. SF was collected from 58 metacarpophalangeal (M...

2025-10-16 | MTBLS1645 | MetaboLights

An extract prepared from species of Paris is the most widely consumed herbal product in China. The genus Paris includes a variety of genotypes with different medicinal component contents but only two are defined as official sources. Closely related species have different medicinal properties beca...

2020-01-13 | MTBLS779 | MetaboLights

Gastrointestinal bacteria interact with the host and each other through various mechanisms, including the production of extracellular vesicles (EVs). However, the composition and potential roles of EVs released by gut archaea are poorly understood. Here, we study EVs produced by four strains of h...

2025-07-01 | MTBLS12422 | MetaboLights
Peroxisomes are versatile single membrane-enclosed cytoplasmic organelles, involved in reactive oxygen species (ROS) and lipid metabolism and diverse other metabolic processes. Peroxisomal disorders result from mutations in Pex genes-encoded proteins named peroxins (PEX proteins) and single peroxiso...
2022-02-02 | MTBLS1887 | MetaboLights
By characterizing physiological changes that occur in warfighters during simulated combat, we can start to unravel the key biomolecular components that are linked to physical and cognitive performance. Viable field-based sensors for the warfighter must be rapid and noninvasive. In an effort to facil...
2023-12-05 | MTBLS5463 | MetaboLights
In order to understand the underline mechanism of SHMT2 (serine hydroxymethyltransferase 2) effect on tumor growth, proteome and metabolome analysis were carried on an engineered HeLa cell line (HeLa-SHMT2-shSHMT2, short as HeLa-Ss), which has inducible SHMT2 over-expression or suppression by treati...
2020-08-20 | MTBLS405 | MetaboLights
Data from PeptideAtlas, [[http://www.peptideatlas.org/PASS/PASS00551 PASS00551]]. File: SBEP_STM_subcell-53c_14Jan11_Doc_10-09-53.mzml. Published as part of . From the Abstract: {{i}} Towards developing a systems-level pathobiological understanding of Salmonella enterica, we performed a subcellular...
ORGANISM(S): Salmonella_phage_c341_uid39795,salmonella_phage_e1_uid29079,salmonella_phage_epsilon34_uid33779,salmonella_phage_fels_1_uid29267,salmonella_phage_phisg_jl2_uid30063,salmonella_phage_se1_uid33483,salmonella_phage_setp3_uid19157,salmonella_phage_st64b_uid14228, Salmonella_enterica_serovar_typhimurium_14028s 
Proximity-based (APEX and BioID) and standard affinity capture proteomics of the mammalian ribosome associated quality control complex
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-01-31 | MSV000082006 | MassIVE
The most important step in any quantitative proteomic pipeline is feature detection (aka peak picking). However, generating quality hand-annotated data sets to validate the algorithms, especially for lower abundance peaks, is nearly impossible. An alternative for creating gold standard data is to si...
ORGANISM(S): Homo sapiens (Human) 
2020-01-24 | PXD000477 | Pride
Proteomic workflows based on nanoLC-MS/MS data-dependent-acquisition analysis have progressed tremendously in recent years due to the technical improvement of mass spectrometers, and now allow to extensively characterize complex protein mixtures. High-resolution and fast sequencing instruments have ...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2015-12-01 | PXD001819 | Pride
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