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TranscriptomicsTranscription profiling of bark from Mexican Lime inoculated with two different isolates of the Citrus Tristeza Virus
The transcriptional response of the Mexican Lime to two different isolates of the Citrus Tristeza Virus was evaluated. Virus Isolates were T305, which provokes severe symptoms in Lime plants, and isolate T385 which does not result in any visible symptoms. Five Lime plants were inoculated with each v...
ORGANISM(S): Citrus aurantifolia 
2007-05-18 | E-MEXP-1106 | biostudies-arrayexpress
MetabolomicsOverexpression of the vascular brassinosteroid receptor BRL3 confers drought resistance without penalizing plant growth

Drought represents a major threat to food security. Mechanistic data describing plant responses to drought have been studied extensively and genes conferring drought resistance have been introduced into crop plants. However, plants with enhanced drought resistance usually display lower growth, hi...

2021-05-17 | MTBLS2289 | MetaboLights
TranscriptomicsAspergillus fumigatus in blood reveals a "just wait and see" resting stage behavior
Objective: We analyzed changes in A. fumigatus gene expression profile at various stages of an in vitro model of aspergillosis to study the adaptation of A. fumigatus to the blood environment. Results: Most of virulence factors described to be involved in aspergillosis were not activated during the ...
ORGANISM(S): Aspergillus fumigatus 
2015-11-24 | E-GEOD-70227 | biostudies-arrayexpress
MetabolomicsA multi-omics dataset of heat-shock response in the yeast RNA binding protein Mip6 (NMR assay)

Gene expression is a biological process regulated at different molecular levels, including chromatin accessibility, transcription, and RNA maturation and transport. In addition, these regulatory mechanisms have strong links with cellular metabolism. Here we present a multi-omics dataset that capt...

2020-02-14 | MTBLS1320 | MetaboLights
TranscriptomicsMicroarray Expression Data from Haematopoietic Differentiated Human Embryonic Stem Cells
The underlying mechanisms which are responsible and govern early haematopoietic differentiation during development are poorly understood. Gene expression comparison between pluripotent human embryonic stem cells and earliest haematopoietic progenitors may reveal novel transcripts and pathways and p...
ORGANISM(S): Homo sapiens 
2012-01-06 | E-GEOD-29115 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat retina after IONT and IONC - time series
retinal ganglion cells die after optic nerve injury, either crush or transection. The molecular causesunderlying this degeneration are largely unkwon; the purpose of this job is to find which (if any) gene regulation triggers RGC death with the final goal of design neuroprotective protocols Experim...
ORGANISM(S): Rattus norvegicus 
2008-10-20 | E-GEOD-9918 | biostudies-arrayexpress
TranscriptomicsIdentification of Yeast Genes that Confer Resistance to Chitosan Oligosaccharide (COS) Using Chemogenomics
Abstract: Chemogenomic fitness assays were combined with a transcriptome analysis to understand both the mode of action and the mechanisms of resistance to Chitosan oligosaccharides (COS). COS are deacetylated chitin compounds, with antimicrobial properties, that are presumed to act by disrupting t...
ORGANISM(S): Saccharomyces cerevisiae 
2012-12-22 | E-GEOD-32888 | biostudies-arrayexpress
TranscriptomicsExpression profiling shows differential functions and provides potential new diagnostic biomarkers for colorectal serrated adenocarcinoma
Our microarray study validates characteristic functions of serrated adenocarcinoma (SAC) reported in the only previous study which was performed on patients from a dissimilar environmental and genetic background and using a different microarray platform. In our study, fascin1 and hippocalcin were va...
ORGANISM(S): Homo sapiens 
2012-10-31 | E-GEOD-36758 | biostudies-arrayexpress
MetabolomicsMetabolomics profiling (GC-MS and LC-MS) for time-course differentiation of pre-B cells-like (B3 cell line) under the controlled induction of the transcription factor Ikaros (STATegra Project)
The main goal of the project is to develop a new generation of bioinformatics resources for the integrative analysis of multiple types of 'omics data. These resources include both novel statistical methodologies as well as user-friendly software implementations. STATegra methods address many aspects...
2016-12-15 | MTBLS283 | MetaboLights
TranscriptomicsMethyome profiling in serrated carcinoma
Serrated adenocarcinoma (SAC) is a recently recognized colorectal cancer (CRC) subtype accounting for 7.5 - 8.7% of CRCs. It has been shown that SAC has a worse prognosis and has different molecular and immunohistochemical features compared to conventional carcinoma (CC) but, to date, there is no st...
ORGANISM(S): Homo sapiens 
2015-06-21 | E-GEOD-68060 | biostudies-arrayexpress
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