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ProteomicsDepletion of melanin exposes Aspergillus flavus conidial surface proteins and alters the surface architecture and virulence.
A. flavus keratitis is one of the predominant fungal infections affecting the tropical parts of the world. Melanin is a virulence factor in numerous pathogenic fungi and the melanin layer maintains the cell wall structure and provides chemical and physical protection to the organism. However, the mo...
ORGANISM(S): Aspergillus flavus FRR 3643 
2024-05-23 | PXD037707 | Pride
Non-melanized conidia Melanized conidia Melanin And surface protein 
ProteomicsConidial Surface associated proteins of Aspergillus flavus and Aspergillus fumigatus
The conidial surface associated proteins of A.flavus and A. fumigatus were extracted using 0.5 M NaCl and identified using shotgun proteomics approach. Incubation of the spores in mQ was used as reference.
ORGANISM(S): Aspergillus fumigatus Af293 Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167) 
2025-01-17 | PXD022824 | Pride
A. flavus Mass spectrometry A. fumigatus Conidial surface 
ProteomicsThe role of RodAp-conserved cysteine residues in the Aspergillus fumigatus conidial surface organization
Immune inertness of Aspergillus fumigatus conidia, an airborne fungal pathogen, is attributed to its surface rodlet-layer made up of RodAp, a protein belonging to the hydrophobin family, characterized by eight conserved cysteine residues forming four disulfide bonding. Earlier, we showed that the co...
ORGANISM(S): Neosartorya fumigata (Aspergillus fumigatus) 
2021-02-18 | PXD020136 | Pride
Conidia Surface proteomics Roda Aspergillus fumigatus Lc-ms/ms 
UnknownMelanin depletion affects Aspergillus flavus conidial surface proteins, architecture, and virulence.
Not available
S-EPMC11004046 | biostudies-literature
UnknownAssembly and disassembly of Aspergillus fumigatus conidial rodlets.
Not available
S-EPMC7389560 | biostudies-literature
ProteomicsConidial rodlets of Aspergillus fumigatus
Aerial conidia of Ascomycetes and Basidiomycetes are coated with an amphipathic hydrophobin layer commonly called rodlet layer, that renders their surface hydrophobic and resist wetting, thus facilitating effective dispersal in the air. Fungal hydrophobins are small secreted proteins with specific...
ORGANISM(S): Aspergillus fumigatus CEA10 
2021-09-08 | PXD008503 | Pride
Aspergillus Label-free proteomic 
UnknownThe Role of RodA-Conserved Cysteine Residues in the Aspergillus fumigatus Conidial Surface Organization.
Not available
S-EPMC7558875 | biostudies-literature
UnknownAspergillus fumigatus conidial surface-associated proteome reveals factors for fungal evasion and host immunity modulation.
Not available
S-EPMC11699518 | biostudies-literature
UnknownA phylogenetic approach to explore the Aspergillus fumigatus conidial surface-associated proteome and its role in pathogenesis.
Not available
S-EPMC10543367 | biostudies-literature
ProteomicsThe puzzling construction of the conidial outer layer of Aspergillus fumigatus
The outer layers of the fungal cell wall are the first barrier facing external challenges. In theinvasive morphotype of the airborne pathogen Aspergillus fumigatus, i.e. conidia, the outer cell wall consists of α-(1,3)-glucan, melanin and proteinaceous rodlets made up by the RodA hydrophobin. The h...
ORGANISM(S): Aspergillus fumigatus CEA10 
2019-01-30 | PXD011734 | Pride
Conida Aspergillus fumigatus Out layer 
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