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ProteomicsA phylogenomic approach to explore the Aspergillus fumigatus conidia surforme and its role in pathogenesis
Aspergillus fumigatus is the most important pulmonary fungal pathogen. Virulence has evolved several times in the section Aspergillii. However, there are species in this section, such as A. fischerii and A. oerlinghausensis, that are very closely related to A. fumigatus but are not reported as patho...
ORGANISM(S): Neosartorya fumigata (Aspergillus fumigatus) Aspergillus lentulus Neosartorya fischeri Aspergillus oerlinghausenensis 
2024-06-26 | PXD031199 | Pride
Conidia Asparaginase Macrophages Aspergilli Surfome 
ProteomicsLC-MS/MS of dithiothreitol-extracted proteins from the insect fungal pathogen Beauveria bassiana conidia
Proteins were extracted using 2 mM DTT from Beauveria bassiana conidia were identified and quantified using Label-free quantitative mass spectrometry.
ORGANISM(S): Beauveria bassiana CGMCC 7.34 
2017-01-04 | PXD004470 | Pride
Llc-ms/ms  dtt-extracted proteins  beauveria bassiana  conidia 
ProteomicsLC-MS/MS of dithiothreitol-extracted proteins from the insect fungal pathogen Beauveria bassiana conidia
Proteins were extracted using 2 mM DTT from Beauveria bassiana conidia were identified and quantified using Label-free quantitative mass spectrometry.
ORGANISM(S): Beauveria bassiana CGMCC 7.34 
2022-03-02 | PXD004474 | Pride
Llc-ms/ms  dtt-extracted proteins  beauveria bassiana  conidia 
ProteomicsProteome characterization of Paracoccidioides lutzii conidia by using label free proteomics
Paracoccidioidomycosis (PCM) is an endemic mycosis in Latin America. The PCM is a systemic disease caused by the thermo dimorphic fungus Paracoccidioides spp, which can exist as mycelia and yeast forms. The mycelia form can be found in environment at temperatures between 18 °C and 25 °C and produces...
ORGANISM(S): Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides brasiliensis) 
2020-09-10 | PXD008649 | Pride
Conidia Paracoccidioidomycosis Proteome Virulence factors 
ProteomicsPhagolysosomal proteomics identifies different macrophage activation profiles in response to Aspergillus fumigatus conidia
An Aspergillus fumigatus infection is initialized by the inhalation and germination of airborne asexual spores (conidia). Alveolar macrophages are the first immune cells to counteract an infection by phagocytosis of conidia and intracellular degradation of the pathogen. However, A. fumigatus circumv...
ORGANISM(S): Neosartorya fumigata (Aspergillus fumigatus) Mus musculus (Mouse) 
2018-03-08 | PXD005724 | Pride
Phagolysosome Macrophages Host-pathogen interaction Aspergillus fumigatus 
TranscriptomicsTranscription profiling of Aspergillus fumigatus hyphae and conidia after incubation with neutrophils from different donors
Hyphae and conidia, representing the two developmental stages of the fungus, were examined separately in this study.

RNA from hyphae or conidia incubated in plasma in RPMI/HEPES without neutrophils was used as reference, and was co-hybridized with the query samples obtained from the correspon...
ORGANISM(S): Aspergillus fumigatus 
2008-09-25 | E-MEXP-1722 | biostudies-arrayexpress
TranscriptomicsTranscription profile of dormant and germinating Aspergillus niger conidia
Genome-wide analysis was performed to assess the transcriptional landscape of germinating A. niger conidia using GeneChips. The metabolism of storage compounds during conidial germination was also examined and compared to the transcript levels from associated genes. The transcriptome of dormant coni...
ORGANISM(S): Aspergillus niger 
2013-05-01 | E-GEOD-42480 | biostudies-arrayexpress
ProteomicsA shotgun proteomics reference map for the alkali-sensitive covalently-linked proteins of the cell wall of A. fumigatus during specific stages of early fungal development (dormant conidia, isotropically expanding conidia, early germ tube emergence and young hyphae).
Four different developmental time points representing the Afu development from dormant conidia into young hyphae (0h, 4h, 6h, 8h) were chosen. Cell walls of the Afu samples were extracted using denaturing methods followed by isolation of solubilized proteins. Samples were processed using filter aide...
ORGANISM(S): Aspergillus fumigatus Af293 
2016-12-20 | PRD000567 | Pride
ProteomicsPhagolysosomal proteomics identifies DHN-melanin-regulated processes in activated macrophage in response to Aspergillus fumigatus conidia
Infection by the human pathogenic fungus Aspergillus fumigatus is initialized by the outgrowth of asexual spores (conidia) into the lung tissue of the immunocompromised host following an inhalation of the airborne conidia. The resident phagocytes, the alveolar macrophages are the first immune cells ...
ORGANISM(S): Neosartorya fumigata (Aspergillus fumigatus) Mus musculus (Mouse) 
2018-03-08 | PXD006134 | Pride
Host-pathogen interactions Aspergillus fumigatus Mycology Lc-ms Phagolysosome Dhn-melanin Macrophage Proteomics 
TranscriptomicsExpression data from dormant and germinating conidia from Aspergillus niger.
Conidia of Aspergillus niger are characterized by a dormant state and are moderate stress-resistant. Upon contact with a moist substrate, germination of conidia occurs by changing from a dormant stabilized state towards a growing vegetative cell. The RNA expression levels of dormant conidia and coni...
ORGANISM(S): Aspergillus niger 
2012-03-13 | E-GEOD-36439 | biostudies-arrayexpress
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