Sort   by:  
 Page size 
UnknownPotential nectin-1 binding site on herpes simplex virus glycoprotein d.
Not available
S-EPMC538551 | biostudies-literature
TranscriptomicsTranscription profiling of human dendritic cells matured by cadherin reveals disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation
The maturation of dendritic cells (DCs) after exposure to microbial products or inflammatory mediators plays a critical role in initiating the immune response. We found that maturation can also occur under steady state conditions, triggered by alterations in E-cadherin-mediated DC-DC adhesion. Sele...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9241 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiles of mouse and human monocyte and dendritic cell subsets (human data)
Dendritic cells (DCs) are critical in mediating immunity to pathogens, vaccines, tumors and tolerance to self. Significant progress has been made in the study of DC subsets in murine models but the translation of these findings to human DC immunobiology has not been fully realized. Murine splenic C...
ORGANISM(S): Homo sapiens 
2012-07-11 | E-GEOD-35457 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiles of mouse and human monocyte and dendritic cell subsets (mouse data)
Dendritic cells (DCs) are critical in mediating immunity to pathogens, vaccines, tumors and tolerance to self. Significant progress has been made in the study of DC subsets in murine models but the translation of these findings to human DC immunobiology has not been fully realized. Murine splenic C...
ORGANISM(S): Mus musculus 
2012-07-11 | E-GEOD-35458 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human dendritic cells and monocytes treated with anti-FcgRIIb
The ability of dendritic cells (DCs) to activate immunity is linked to their maturation status. In prior studies we have shown that selective antibody-mediated blockade of inhibitory FcgRIIB receptor on human DCs in the presence of activating immunoglobulin (Ig) ligands leads to DC maturation and en...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7509 | biostudies-arrayexpress
TranscriptomicsHigh mitochondrial respiration and glycolytic capacity represent a metabolic phenotype of human tolerogenic dendritic cells
Human monocyte-derived dendritic cells (moDCs) have been used as an in vitro model for studying tolerance and immunity. However, the underlying metabolic states of tolerogenic (dexamethasone and vitamin D3-treated), immature and immunogenic (mature, LPS-treated) moDCs have not been completely charac...
ORGANISM(S): Homo sapiens 
2015-05-08 | E-GEOD-52894 | biostudies-arrayexpress
UnknownStructure of unliganded HSV gD reveals a mechanism for receptor-mediated activation of virus entry.
Not available
S-EPMC1356314 | biostudies-literature
UnknownMicroenvironmental and cell intrinsic factors governing human cDC2 differentiation and monocyte reprogramming.
Not available
S-EPMC10395083 | biostudies-literature
TranscriptomicsCD2 distinguishes two subsets of human plasmacytoid dendritic cells with distinct phenotype and functions
Plasmacytoid dendritic cells (pDCs) are key regulators of anti-viral immunity. They rapidly secrete IFN-alpha and cross-present viral antigens thereby launching adaptive immunity. Here we show that activated human pDCs inhibit replication of cancer cells, and kill them in a contact dependent fashion...
ORGANISM(S): Homo sapiens 
2009-05-21 | E-GEOD-15215 | biostudies-arrayexpress
MetabolomicsIntegrated Exposomics/Metabolomics for Rapid Exposure and Effect Analyses

The totality of environmental exposures and lifestyle factors, commonly referred to as the exposome, are poorly understood. Measuring the myriad of chemicals that humans are exposed to is immensely challenging and identifying disrupted metabolic pathways is even more complex. Here, we present a n...

2023-10-26 | MTBLS4556 | MetaboLights
Sort   by:  
 Page size