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GenomicsCRUK-ICGC Prostate Cancer Group Study
Prostate cancer somatic genomic sequencing data generated from 2011 onwards under auspices of the International Cancer Genome Consortium Prostate Cancer UK consortium (CRUK-ICGC Prostate Group), co-led by Colin Cooper and Ros Eeles, with other Principal Investigators (Brewer, Neal, Bova, McDermott, ...
EGAS00001000262 | EGA
TranscriptomicssiRNA knockdown of ribosomal protein gene RPL19 abrogates the aggressive phenotype of human prostate cancer
Ribosomal protein RPL19 is an integral component of eukaryotic ribosomes and universally involved in protein synthesis. Although consistently stableM-BM- in normal cells, RPL19 transcription is relatively elevated in prostate cancer. Using siRNA, we inhibited RPL19 transcription and demonstrated th...
ORGANISM(S): Homo sapiens 
2011-12-08 | E-GEOD-26774 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wheat to identify genotypic differences in water soluble carbohydrate metabolism in stem
Water soluble carbohydrates (WSC, composed of mainly fructans, sucrose, glucose and fructose) deposited in wheat stems are important carbon sources for grain filling. Variation in stem WSC concentrations among wheat genotypes is one of the genetic factors influencing grain weight and yield under wat...
ORGANISM(S): Triticum aestivum 
2008-10-26 | E-GEOD-9767 | biostudies-arrayexpress
GenomicsEGAS00001000262-sc-20131030 - samples
Whole genome DNA sequencing was used to decrypt the phylogeny of multiple samples from distinct areas of cancer and morphologically normal tissue taken from the prostates of 3 men. For each of three different prostates, multiple tumour samples (4, 5, and 3 depending on the case) and one normal tissu...
EGAD00001000689 | EGA
TranscriptomicsBlood mRNA expression signatures derived from unsupervised analyses identify prostate cancers with poor outcome
Background: Inter-patient prostate cancer (PrCa) heterogeneity results in highly variable patient outcomes. Multi-purpose biomarkers to dissect this heterogeneity are urgently required to improve treatment and accelerate drug development in PrCa. Circulating biomarkers are most practical for evaluat...
ORGANISM(S): Homo sapiens 
2012-10-15 | E-GEOD-37199 | biostudies-arrayexpress
GenomicsEGAS00001000262-sc-20170314 - samples
Whole Genome Sequencing Illumina HiSeq data from 111 men with prostate cancer. Samples were taken from primary tissue obtained at prostatectomy (target sequencing depth 50X) with matched blood control (target sequencing depth 30X). This data is from batches 4 to 6.
EGAD00001003225 | EGA
GenomicsEGAS00001000262-sc-20141219 - samples
Whole Genome Sequencing Illumina HiSeq data from 95 men with prostate cancer. Samples were taken from primary tissue obtained at prostatectomy (target sequencing depth 50X) with matched blood control (target sequencing depth 30X). This data is from batches 1 to 3 and is the bulk of the data used in ...
EGAD00001001116 | EGA
GenomicsEGAS00001000262-sc-20140722b - samples
Whole Genome Sequencing Illumina HiSeq data from 20 men with prostate cancer. 20 samples were taken from primary tissue obtained at prostatectomy (target sequencing depth 50X) with matched blood control (target sequencing depth 30X). These were submitted for use in the ICGC Pan-Cancer Analysis of Wh...
EGAD00001000892 | EGA
GenomicsEGAS00001000262-sc-2023-03-27T08:52:54Z - samples
This dataset includes Illumina EPIC Capture Sequencing Data of 376 samples from 188 men with prostate cancer. Samples were taken from primary tissue obtained at prostatectomy, with matched pathologically assessed non-cancer control material. This DNA methylation data includes donors and samples incl...
EGAD00001010184 | EGA
Genomicsena-DATASET-SC-16-09-2014-14:22:12:125-153 - samples
Description not provided
EGAD00001001014 | EGA
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