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TranscriptomicsA gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK.
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease consisting of emphysema, small airway obstruction, and/or chronic bronchitis that results in significant loss of lung function over time. METHODS: In order to gain insights into the molecular pathways underlying prog...
ORGANISM(S): Homo sapiens 
2012-09-11 | E-GEOD-27597 | biostudies-arrayexpress
TranscriptomicsThe effect of periconceptional micronutrient supplementation on offspring DNA methylation
The effect of pre and periconceptional multiple micronutrient supplementation on methylation of CpG loci within CpG islands associated with 14,000 genes across the human genome has been investigated in the offspring of a cohort of Gambian women participating in a controlled double blinded trial. Met...
ORGANISM(S): Homo sapiens 
2012-03-15 | E-GEOD-34257 | biostudies-arrayexpress
Genomicsnative Tn-seq analysis of ISAba13 in Acinetobacter baumannii AB5075
The experiment contains native Tn-seq data for Acinetobacter baumannii strain AB5075 with different genetic alterations. The strain was grown at 37 degrees in LB medium and genomic DNA was isolated. We then used PCR to select for DNA regions containing a junction between ISAba13 and chromosomal DNA....
ORGANISM(S): Acinetobacter baumannii 
2024-07-15 | E-MTAB-13792 | biostudies-arrayexpress
Genomicsnative Tn-seq analysis of insH3 in Escherichia coli
The experiment contains native Tn-seq data for Escherichia coli strain MG1655. The strain was grown at 37 degrees in LB medium and genomic DNA was isolated. We then used PCR to select for DNA regions containing a junction between insH3 and chromosomal DNA. Libraries were then prepared using these DN...
ORGANISM(S): Escherichia coli 
2024-07-15 | E-MTAB-13793 | biostudies-arrayexpress
GenomicsEGAS00001000262-sc-20131030 - samples
Whole genome DNA sequencing was used to decrypt the phylogeny of multiple samples from distinct areas of cancer and morphologically normal tissue taken from the prostates of 3 men. For each of three different prostates, multiple tumour samples (4, 5, and 3 depending on the case) and one normal tissu...
EGAD00001000689 | EGA
GenomicsWhole Cell Extract
Most human genes are loaded with promoter proximally paused RNA polymerase II (RNAP II) molecules that are poised for release into productive elongation by P-TEFb. Gdown1, a protein that renders RNAP II responsive to mediator, is involved in RNAP II elongation control. During in vitro transcription ...
ORGANISM(S): Homo sapiens 
2012-02-21 | E-GEOD-35882 | biostudies-arrayexpress
GenomicsFunctional association of Gdown1 with RNA Polymerase II in Human
Most human genes are loaded with promoter proximally paused RNA polymerase II (RNAP II) molecules that are poised for release into productive elongation by P-TEFb. Gdown1, a protein that renders RNAP II responsive to mediator, is involved in RNAP II elongation control. During in vitro transcription ...
ORGANISM(S): Homo sapiens 
2012-01-13 | E-GEOD-32442 | biostudies-arrayexpress
GenomicsCRUK-ICGC Prostate Cancer Group Study
Prostate cancer somatic genomic sequencing data generated from 2011 onwards under auspices of the International Cancer Genome Consortium Prostate Cancer UK consortium (CRUK-ICGC Prostate Group), co-led by Colin Cooper and Ros Eeles, with other Principal Investigators (Brewer, Neal, Bova, McDermott, ...
EGAS00001000262 | EGA
GenomicsRenormalization of GSE32442 and GSE33128
Raw data from GSE32442 and GSE33128 and the input dataset for GSE32442 were renormalized by using reads per million. 11 samples from GSE32442 and GSE33128
ORGANISM(S): Homo sapiens 
2012-02-21 | E-GEOD-35878 | biostudies-arrayexpress
GenomicsRenormalization of GSE32442 and GSE33128 plus 1 control sample
This SuperSeries is composed of the following subset Series: GSE35878: Renormalization of GSE32442 and GSE33128 GSE35882: Whole Cell Extract Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-02-21 | E-GEOD-35886 | biostudies-arrayexpress
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