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TranscriptomicsImpact of brief exercise on peripheral blood NK cell gene and microRNA expression in young adults
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-04-02 | E-GEOD-41915 | biostudies-arrayexpress
TranscriptomicsChanges in eutopic endometrial gene expression during the progression of experimental endometriosis in the baboon, Papio anubis
Endometriosis is associated with aberrant gene expression in the eutopic endometrium of women with disease. To determine if the development of endometriotic lesions directly impacts eutopic endometrial gene expression, we sequentially analyzed the eutopic endometrium across the time course of diseas...
ORGANISM(S): Papio anubis 
2015-08-27 | E-GEOD-72428 | biostudies-arrayexpress
TranscriptomicsMyotonic dystrophy type 1 (DM1) leads to altered mRNA expression in heart tissue
Myotonic dystrophy type 1 (DM1) is a dominantly inherited disease that affects multiple organ systems. Cardiac dysfunction is the second leading cause of death in DM1. We quantified gene expression in heart tissue from a heart-specific DM1 mouse model (EpA960/MCM) which inducibly expresses human DMP...
ORGANISM(S): Mus musculus 
2014-01-24 | E-GEOD-48991 | biostudies-arrayexpress
UnknownMethotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good Response Randomized Controlled Trial.
Not available
S-EPMC4486345 | biostudies-literature
TranscriptomicsArctic charr exposed to acute thermal stress
Arctic charr is an especially attractive aquaculture species given that it features the desirable tissue traits of other salmonids, but can be bred and grown at inland freshwater tank farms year round. It is therefore of interest to develop upper temperature tolerant (UTT) strains of Arctic charr to...
ORGANISM(S): Salmo salar 
2011-06-01 | E-GEOD-26306 | biostudies-arrayexpress
TranscriptomicsHigh gene expression of inflammatory markers and IL-17A in Atlantic salmon vaccinated with oil-adjuvanted vaccines
Two decades after the introduction of oil-based vaccines in the control of bacterial and viral diseases in farmed salmonids, the mechanisms of induced side effects manifested as intra-abdominal granulomas remain unresolved. Side effects have been associated with generation of auto-antibodies and aut...
ORGANISM(S): Salmo salar 
2007-08-20 | E-GEOD-8826 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression in the hippocampus of dab1 homozygous mutants in C57BL/6 and BALB/c mice.
Differential gene expression in the hippocampus was analyzed between Dab1 and wild type mice on the C57BL/6 and BALB/c mouse strains. Total RNA obtained from isolated hippocampus at postnatal day 19 was analysed for gene expression between C57BL6 and BALB/c wild type or dab1 mutant mice. Three sampl...
ORGANISM(S): Mus musculus 
2011-06-01 | E-GEOD-22044 | biostudies-arrayexpress
TranscriptomicsDifferential expression of 24,426 human alternative splicing events and predicted cis-regulation in 48 tissues
Alternative pre-messenger RNA splicing impacts development, physiology, and disease, but its regulation in humans is not well understood, partially due to the limited scale to which the expression of specific splicing events has been measured. We generated the first genome-scale expression compendi...
ORGANISM(S): Homo sapiens 
2008-08-15 | E-GEOD-11863 | biostudies-arrayexpress
TranscriptomicsFunctional Antagonism Between CELF and Mbnl Proteins in Cytoplasm and Nucleus [RNA Bind-N-Seq]
The CUG-BP and ETR-3-like factor 1 (Celf1) RNA binding protein plays an important role in heart and muscle development, and is over-expressed in the disease myotonic dystrophy. Celf1 has known roles in regulation of RNA splicing, RNA stability, and protein translation. To identify transcriptome-wi...
ORGANISM(S): synthetic construct 
2015-04-13 | E-GEOD-67337 | biostudies-arrayexpress
TranscriptomicsC9ORF72 GGGGCC expanded repeats produce splicing dysregulation which correlates with disease severity in amyotrophic lateral sclerosis [HuEx-1_0-st]
Objective: An intronic GGGGCC-repeat expansion of C9ORF72 is the most common genetic variant of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. The mechanism of neurodegeneration is unknown, but a direct effect on RNA processing mediated by RNA foci transcribed from the repeat seque...
ORGANISM(S): Homo sapiens 
2015-05-08 | E-GEOD-68607 | biostudies-arrayexpress
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