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Pediatric osteosarcomas are characterized by an unusually dilated endoplasmic reticulum (ER). Our analysis of RNA expression data from 108 patient tumor samples and patient-derived xenografts (PDXs) revealed the overwhelming majority of these tumor have reduced expression of four COPII vesicle comp...
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD031620 | Pride
Normal neural development is essential for the formation of neuronal networks and brain function. cTAGE5/MEA6 plays a critical role in the secretion of proteins. However, its roles in the transport of non-secretory cellular components and in brain development remain unknown. Here, we show that cTAGE...
ORGANISM(S): Mus musculus (Mouse) 
2018-09-18 | PXD010386 | Pride
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