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Corpus luteum (CL) is an endocrine structure that undergoes substantial changes over short intervals during the bovine reproductive (estrous) cycle. These changes are regulated by a vast array of signaling molecules, mainly proteins, that govern reproduction. We collected a comprehensive set of CLs ...
ORGANISM(S): Bos taurus (Bovine) 
2026-02-19 | PXD069851 | Pride
Luteolysis of the corpus luteum (CL) during non-fertile cycles involves a cessation of progesterone (P4) synthesis (functional regression) and subsequent structural remodeling. The molecular processes responsible for initiation of luteal regression in the primate CL are poorly defined. Therefore, a ...
ORGANISM(S): Macaca mulatta 
This study was designed to provide a genome-wide analysis of the effects of luteinizing hormone (LH) ablation/replacement versus steroid ablation/replacement on gene expression in the developed corpus luteum (CL) in primates during the menstrual cycle. Naturally cycling, female rhesus monkeys were l...
ORGANISM(S): Macaca mulatta 
miRNAs in the porcine corpus luteum
Observational data suggest that women conceiving without a corpus luteum are at higher risk of developing preeclampsia. While the underlying mechanisms remain unclear, the absence of corpus luteum-derived secretory products may be a contributing factor. This study investigates whether the plasma pro...
ORGANISM(S): Homo sapiens (Human) 
2025-09-30 | PXD067974 | Pride
Transcriptomic profile of porcine corpus luteum after PPAR gamma ligands treatment
The corpus luteum plays a critical role in reproduction because it is the primary source of circulating progesterone. This study aimed to determine the in vitro effect of peroxisome proliferator-activated receptor gamma (PPARγ) ligands on the transcriptome genes expression in the porcine corpus lute...
ORGANISM(S): Sus scrofa 
In order to indentify genes regulated by eCG, and involved in CL development and progesterone increases, the transcriptome was evaluated using the microarray technology Cows (Bos indicus) were divided into control, stimulated and superovulated groups. The stimulated group received 400 IU of eCG on...
ORGANISM(S): Bos indicus 
Effect of PGF2α on the transcriptome of the bovine corpus luteum
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