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TranscriptomicsIntegrative approach for prioritizing cancer genes in sporadic colon cancer
The current multistep carcinogenesis models of colon cancer do not fully capture the genetic heterogeneity of the disease, which is additionally complicated by the presence of passenger and driver genetic alterations. The aim of the present study was to select in the context of this significant hete...
ORGANISM(S): Homo sapiens 
2010-04-10 | E-GEOD-16125 | biostudies-arrayexpress
ProteomicsFibroblasts’ secretome from calcified and non-calcified dermis in Pseudoxanthoma elasticum differently contributes to elastin calcification.
Pseudoxanthoma elasticum (PXE) is characterized by ectopic calcification, however, despite the widely spread effect of pro/anti-calcifying systemic factors associated with the genetic metabolic condition, it not known why elastic fibers (EF) in the same patient are mainly fragmented or highly minera...
ORGANISM(S): Homo sapiens (Human) 
2024-04-18 | PXD048829 | Pride
Fibroblasts  elastin  mineralization  proteomics  pxe 
ProteomicsProteomic analysis of serum small extracellular vesicles of individual mice for longitudinal investigations
Characterization of small extracellular vesicles (sEV) from individual mice for the longitudinal investigation of proteome changes in a mouse model of Glioblastoma Multiforme (GBM). We first compared precipitation and size exclusion chromatography (SEC) for sEV purification from 100ul of mouse serum...
ORGANISM(S): Mus musculus (Mouse) 
2020-11-30 | PXD016473 | Pride
Glioblastoma Proteomics Size exclusion chromatography Small extracellular vesicles Serum Mouse Biomarker discovery 
ProteomicsNeuron-Derived Exosomes as a tool for the study of Parkinson disease: a rapid workflow for morphology, miRNA and proteomic characterization.Neuron-Derived Exosomes as a tool for the study of Parkinson disease: a rapid workflow for morphology, miRNA and proteomic characterization.Neuron-Derived Exosomes as a tool for the study of Parkinson disease: a rapid workflow for morphology, miRNA and proteomic characterization.
Neuron derived exosomes have been enriched from plasma using L1CAM antigen. Vesicles were enriched from plasma of Parkinson Disease patients and controls. The NDE morphology was observed by transmission electron microscope (TEM). miRNA-155 content was studied both in PD-NDE and control-NDE. LC-MS/MS...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD020794 | Pride
Proteomics Parkinson disease Neuron derived exosomes Plasma L1cam 
UnknownRivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial.
Not available
S-EPMC6662613 | biostudies-literature
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