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MetabolomicsUntargeted LC-MS metabolomic studies of Asteraceae species to discover inhibitors of Leishmania major dihydroorotate dehydrogenase

INTRODUCTION: Interesting data about the family Asteraceae as a new source of Leishmania major dihydroorotate dehydrogenase (LmDHODH) inhibitors are presented. This key macromolecular target for parasites causing neglected diseases catalyzes the fourth reaction of the de novo pyr...

2019-10-14 | MTBLS722 | MetaboLights
TranscriptomicsWhole genome expression profile of dsap18 mutant Drosophila melanogaster embryos
SAP18 is a highly evolutionarily conserved protein found in all eukaryotic organisms from Saccharomycces cerevisiae to humans. It has been proposed to be involved in multiple cellular processes, from gene regulation to mRNA processing, playing different cellular functions, such as cell fate control ...
ORGANISM(S): Drosophila melanogaster 
2011-01-18 | E-GEOD-17066 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae (budding yeast) mutants reveals Isc1p plays a key role in hydrogen peroxide resistance and chronological lifespan through modulation of iron levels and programmed cell death
Changes in the transcriptome of Isc1p deficient mutants. The inositolphosphosphingolipid phospholipase C (Isc1p) of Saccharomyces cerevisiae belongs to the family of neutral sphingomyelinases that generates the bioactive sphingolipid ceramide. In this work the role of Isc1p in oxidative stress resis...
ORGANISM(S): Saccharomyces cerevisiae 
2008-02-05 | E-MEXP-1136 | biostudies-arrayexpress
UnknownA Novel Biochar from Agro-Industrial Waste: Synthesis, Characterization, and Application for Acetylsalicylic Acid Removal.
Not available
S-EPMC12676325 | biostudies-literature
MetabolomicsDynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression

Metabolic reprogramming is critical for tumor initiation and progression. However, the exact impact of specific metabolic changes on cancer progression is poorly understood. Here, we integrate multimodal analyses of primary and metastatic clonally-related clear cell renal cancer cells (ccRCC) gro...

2022-12-08 | MTBLS5615 | MetaboLights
UnknownA Randomized Controlled Trial Assessing the Release of Circulating Tumor and Mesenchymal Cells in No-Touch Radical Nephrectomy.
Not available
S-EPMC11545310 | biostudies-literature
ProteomicsBreast muscle proteome of broilers fed with 15 % dietary incorporation of Limnospira platensis
The present study investigates the impact of dietary inclusion of 15% extruded L. platensis, with or without enzyme supplementation, on the broiler breast muscle proteome. Using a label-based comparative proteomics approach, this study aims to uncover key protein changes and associated biological pr...
ORGANISM(S): Gallus gallus (Chicken) 
2025-10-06 | PXD064230 | Pride
Extrusion Muscle proteome Broilers L.platensis 
UnknownLong-Term Biochemical and Cardiovascular Profiles 3-6 Years After Preeclampsia: Impact of Angiogenic Imbalance During Pregnancy.
Not available
S-EPMC12692977 | biostudies-literature
UnknownLong-Term Cardiopulmonary Function After COVID-19-Associated Acute Respiratory Distress Syndrome: A Multicenter Case-Control Study.
Not available
S-EPMC12440408 | biostudies-literature
UnknownPlatelet-Rich Plasma Injections Do Not Improve the Recovery After Arthroscopic Partial Meniscectomy: A Double-Blind Randomized Controlled Trial.
Not available
S-EPMC11542319 | biostudies-literature
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