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UnknownA cotranslational ubiquitination pathway for quality control of misfolded proteins.
Not available
S-EPMC3654026 | biostudies-literature
UnknownmTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide.
Not available
S-EPMC3020639 | biostudies-literature
ProteomicsCUL4A-DDB1-DCAF10 is an n-recognin for Nt-acetylated Src kinases
cotranslational n-terminal modifications such as methionine excision, acetylation, and myristoylation contribute to protein stability, localization and three-dimensional folding. Disruption of these modifcations expose short n-terminal degron motifs that ultimately trigger protein degradation throug...
ORGANISM(S): Homo sapiens (Human) 
2025-12-04 | PXD061095 | Pride
N-t acetylation Sfks N-degron dcaf10 Ubiquitination Nt- myristoylation Cotranslational modifications N-recognin 
ProteomicsA new role for the DEAD-box RNA helicase DDX3 in co-translational protein quality control
DEAD-box RNA helicases are central players in RNA metabolism, however, their role in translation regulation is largely unexplored in parasitic protozoa. Here, we have investigated the role of DDX3 RNA helicase in ribosome-associated protein quality control in Leishmania. We show that ribosomes move ...
ORGANISM(S): Leishmania infantum 
2021-07-23 | PXD020667 | Pride
Ribosome Leishmania infantum Ddx3 Label-free quantitative proteomics Cotranslational protein ubiquitination Orbitrap fusion 
UnknownDistinct types of translation termination generate substrates for ribosome-associated quality control.
Not available
S-EPMC5001609 | biostudies-literature
UnknownRole of Hsc70 binding cycle in CFTR folding and endoplasmic reticulum-associated degradation.
Not available
S-EPMC3154877 | biostudies-literature
UnknownCdc48-associated complex bound to 60S particles is required for the clearance of aberrant translation products.
Not available
S-EPMC3612664 | biostudies-literature
UnknownAssessment of Sacsin Turnover in Patients With ARSACS: Implications for Molecular Diagnosis and Pathogenesis.
Not available
S-EPMC8665432 | biostudies-literature
UnknownDonor-Specific Transcriptomic Analysis of Alzheimer's Disease-Associated Hypometabolism Highlights a Unique Donor, Ribosomal Proteins and Microglia.
Not available
S-EPMC7772516 | biostudies-literature
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