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TranscriptomicsTranscription profiling of NIH3T3 cells treated with platelet-derived growth factor and Src kinase inhibitors to identify immediate early genes that are induced by PDGF through Src family kinases and other kinases.
This experiment was performed to identify immediate early genes that were induced by PDGF specifically through Src family kinases (SFKs), MEK1/2, or PI 3-K.
ORGANISM(S): Mus musculus 
2007-09-22 | E-GEOD-2196 | biostudies-arrayexpress
GenomicsSFKs overexpression suffices to change the gene expression landscape in unstimulated BJAB cells
SFKs overexpression suffices to change the gene expression landscape in unstimulated BJAB cells
PRJNA877225 | ENA
TranscriptomicsPDGF induction of immediate early genes in NIH3T3 cells
This experiment was performed to identify immediate early genes that were induced by PDGF specifically through Src family kinases (SFKs), MEK1/2, or PI 3-K. Keywords: repeat sample
ORGANISM(S): Mus musculus 
2005-02-23 | GSE2196 | GEO
ProteomicsSrc heterodimerically activates Lyn or Fyn to serve as targets for esophageal squamous cell carcinoma (ESCC) diagnosis and treatment
we combined phosphoproteomics and several cellular and molecular biologic strategies to identify that Src specifically interacted with the members of Src-family kinases (SFKs), such as Fyn or Lyn to form heterodimers, and subsequently phosphorylate the tyrosine sites in SH2 and kinase domains, which...
ORGANISM(S): Homo Sapiens 
2022-03-15 | PXD032306 |
TranscriptomicsCrk mediates Csk-Hippo signaling independently of Yap tyrosine phosphorylation to induce cell competition
Src family kinases (SFKs), including Src, Fyn and Yes, play important roles in development and cancer. Despite being first discovered as the Yes-associated protein, the regulation of Yap by SFKs remains poorly understood. Here, through single-cell analysis and genetic lineage tracing, we show that t...
ORGANISM(S): Mus musculus 
2025-01-19 | GSE253784 | GEO
TranscriptomicsSFKs overexpression suffices to change the gene expression landscape in unstimulated BJAB cells
Whole transcriptome sequencing of untreated BJAB cells, and BJAB cells after inducing the ectopic expression of Lck or Lyn
ORGANISM(S): Homo sapiens 
2023-09-13 | GSE212759 | GEO
UnknownGender-different effect of Src family kinases antagonism on photophobia and trigeminal ganglion activity.
Not available
S-EPMC11468534 | biostudies-literature
UnknownSrc Family Kinases as Therapeutic Targets in Advanced Solid Tumors: What We Have Learned so Far.
Not available
S-EPMC7352436 | biostudies-literature
UnknownCsk-homologous kinase (Chk) is an efficient inhibitor of Src-family kinases but a poor catalyst of phosphorylation of their C-terminal regulatory tyrosine.
Not available
S-EPMC5547543 | biostudies-literature
UnknownMammalian Pragmin regulates Src family kinases via the Glu-Pro-Ile-Tyr-Ala (EPIYA) motif that is exploited by bacterial effectors.
Not available
S-EPMC3169139 | biostudies-literature
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