Cox C S CS - OmicsDI

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center for biochemistry, University of cologne (2)
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Division of Applied Functional Genomics, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany (1)
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MOE Key Laboratory of Evolution & Marine Biodiversity and Institute of Evolution & Marine Biodiversity, Ocean University of China (1)
NHMRC Senior Research Fellow Department of Biochemistry and Molecular Biology | Faculty of Medicine, Dentistry and Health Sciences Level 2 South, Bio21 Molecular Science and Biotechnology Institute, 30 Flemington Road The University of Melbourne, Victoria 3010 Australia (1)
NHMRC Senior Research Fellow Department of Biochemistry and Molecular Biology | Faculty of Medicine, Dentistry and Health Sciences Level 2 South, Bio21 Molecular Science and Biotechnology Institute, 30 Flemington Road The University of Melbourne, Victoria 3010 Australia (1)
Osnabrueck University Department of Biology/Chemistry Bioanalytical Chemistry Section (1)
Rudolf Virchow Center, Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany (1)
The Walter and Eliza Hall Institute (1)

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Genetic disruption of COX-1 inhibits multiple oncogenic pathways

We performed RNA sequencing in isogenic models of COX-1 proficient (OV3/SCR) and COX-1 deficient (OV3/COX1KD) OVCAR-3 ovarian cancer cells. COX-1 knockdown was associated with a coordinated anti-oncogenic phenotype, with growth, angiogenesis, migration/invasion, and epithelial-mesenchymal transition...

ORGANISM(S): Homo sapiens

2015-06-22 | E-GEOD-66173 | biostudies-arrayexpress

Next generation sequencing profiling identifies miR-574-3p and miR-660-5p as potential novel prognostic markers for breast cancer

Prognostication of Breast Cancer (BC) relies largely on traditional markers such as hormone or growth factors but due to their suboptimal specificities, it is challenging to identify the subset of patients who are likely to undergo recurrence and markers of higher specificity are sought to guide the...

ORGANISM(S): Homo sapiens

2016-03-02 | E-GEOD-68085 | biostudies-arrayexpress

Functional characterization of C. elegans Y-box binding proteins reveals tissue-specific functions and a critical role in the formation of polysomes (RIP-Seq)

We present a basic characterization of the function of Y-box binding proteins (YBPs) in C. elegans. YBPs in other organisms are known RNA-binding proteins. Our global analysis of associated mRNAs supports a role of YBPs as general mRNA binders in C.elegans. FLAG IPs were performed on transgenic anim...

ORGANISM(S): Caenorhabditis elegans

2015-01-08 | E-GEOD-62856 | biostudies-arrayexpress

Whole genome bisulfite sequencing of idm1, rdd, ros1 mutants and Col-0 WT

Using whole genome bisulfite sequencing to provide single-base resulution of DNA methylation status in ros1, idm1, and rdd mutants and identify hypermethylated regions comparing to wild type Arabidopsis plants. Examination of 3 different mutants' methylome. 8 samples (3 mutants, 1 WT, each has two b...

ORGANISM(S): Arabidopsis thaliana

2012-06-17 | E-GEOD-33071 | biostudies-arrayexpress

Pyogenic Liver Abscess is Associated With Increased Risk of Acute Kidney Injury: A Nationwide Population-Based Cohort Study.

Not available

S-EPMC4998258 | biostudies-literature

Transcriptome profiling in 6-hydroxydopamine hemiparkinsonian rats reveals methamphetamine-mediated dopamine-independent changes in striatal gene expression.

Unilateral injections of 6-hydroxydopamine into the medial forebrain bundle (MFB) is used extensively as a model of Parkinson’s disease. The present experiments examined whether a single injection of methamphetamine (METH) (2.5 mg/kg) could still influence striatal gene expression after 6-hydroxydop...

ORGANISM(S): Rattus norvegicus

2010-09-21 | E-GEOD-24233 | biostudies-arrayexpress

Gene expression in nontumoral liver tissue and recurrence-free survival in hepatitis C virus-positive HCC

Background/Aims: Recurrence-free survival (RFS) following curative resection of hepatocellular carcinoma (HCC) in subjects with hepatitis C virus (HCV) infection is highly variable. Traditional clinico-pathological endpoints are recognized as weak predictors of RFS. It has been suggested that gene e...

ORGANISM(S): Homo sapiens

2010-04-14 | E-GEOD-17856 | biostudies-arrayexpress

Safety, immunogenicity and duration of protection of the RTS,S/AS02(D) malaria vaccine: one year follow-up of a randomized controlled phase I/IIb trial.

Not available

S-EPMC2973956 | biostudies-literature

Androgen receptor gene aberrations in circulating cell-free DNA: biomarkers of therapeutic resistance and response in castration-resistant prostate cancer

aCGH experiment on cell-free DNA collected from the plasma of patients with castration-resistant prostate cancer. No replicates. castration-resistant prostate cancer vs male reference DNA

ORGANISM(S): Homo sapiens

2015-03-09 | E-GEOD-61134 | biostudies-arrayexpress

Total Synthesis and Anti-inflammatory Activity of Asperjinone and Asperimide C.

Not available

S-EPMC11348413 | biostudies-literature

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