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ProteomicsAfrican swine fever virus protein CP204L is involved in endosomal trafficking and interacts with the VPS39 subunit of the HOPS complex
African swine fever virus (ASFV) is a large DNA virus causing a highly contagious disease in domestic and wild boar, for which no treatment is available. ASFV vaccine development is hindered by large gaps in knowledge considering virus protein function and virus-host interaction. This study shows th...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2023-01-23 | PXD035695 | Pride
Cp204l Hops complex Asfv Vps39 Virus-host ppi 
UnknownSNX32 is a host restriction factor that degrades African swine fever virus CP204L via the RAB1B-dependent autophagy pathway.
Not available
S-EPMC10804981 | biostudies-literature
UnknownCP204L Is a Multifunctional Protein of African Swine Fever Virus That Interacts with the VPS39 Subunit of the Homotypic Fusion and Vacuole Protein Sorting Complex and Promotes Lysosome Clustering.
Not available
S-EPMC9972913 | biostudies-literature
UnknownInsights into the Role of VPS39 and Its Interaction with CP204L and A137R in ASFV Infection.
Not available
S-EPMC11437485 | biostudies-literature
UnknownEfficient inhibition of African swine fever virus replication by CRISPR/Cas9 targeting of the viral p30 gene (CP204L).
Not available
S-EPMC5780455 | biostudies-literature
ProteomicsInsights into the role of VPS39 and its interaction with CP204L and A137R in ASFV infection
The African swine fever virus (ASFV) is a large and complex DNA virus that causes a highly le-thal disease in swine, for which no antiviral drugs or vaccines are currently available. Studying viral–host protein-protein interactions advances our understanding of the molecular mecha-nisms underlying v...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2024-09-17 | PXD054169 | Pride
African swine fever virus  protein-protein interaction  virus-host interaction 
UnknownIdentification of an Immunodominant B-Cell Epitope in African Swine Fever Virus p30 Protein and Evidence of p30 Antibody-Mediated Antibody Dependent Cellular Cytotoxicity.
Not available
S-EPMC11125664 | biostudies-literature
UnknownDevelopment of an Effective Double Antigen Sandwich ELISA Based on p30 Protein to Detect Antibodies against African Swine Fever Virus.
Not available
S-EPMC9609742 | biostudies-literature
UnknownA new vaccination regimen using adenovirus-vectored vaccine confers effective protection against African swine fever virus in swine.
Not available
S-EPMC10348041 | biostudies-literature
UnknownAfrican swine fever virus isolate, Georgia, 2007.
Not available
S-EPMC2634662 | biostudies-literature
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