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ProteomicsAfrican swine fever virus protein CP204L is involved in endosomal trafficking and interacts with the VPS39 subunit of the HOPS complex
African swine fever virus (ASFV) is a large DNA virus causing a highly contagious disease in domestic and wild boar, for which no treatment is available. ASFV vaccine development is hindered by large gaps in knowledge considering virus protein function and virus-host interaction. This study shows th...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2023-01-23 | PXD035695 | Pride
Cp204l Hops complex Asfv Vps39 Virus-host ppi 
GenomicsmRNA expression data for VPS39-silenced human muscle cells and controls
mRNA expression data for VPS39-silenced human muscle cells and controls
PRJNA661033 | ENA
GenomicsDNA methylation data for VPS39-silenced human muscle cells and controls
DNA methylation data for VPS39-silenced human muscle cells and controls
PRJNA701306 | ENA
ProteomicsInsights into the role of VPS39 and its interaction with CP204L and A137R in ASFV infection
The African swine fever virus (ASFV) is a large and complex DNA virus that causes a highly le-thal disease in swine, for which no antiviral drugs or vaccines are currently available. Studying viral–host protein-protein interactions advances our understanding of the molecular mecha-nisms underlying v...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2024-09-17 | PXD054169 | Pride
African swine fever virus  protein-protein interaction  virus-host interaction 
UnknownVps39 is required for ethanolamine-stimulated elevation in mitochondrial phosphatidylethanolamine.
Not available
S-EPMC7209980 | biostudies-literature
Methylation profilingDNA methylation data for VPS39-silenced human muscle cells and controls
DNA methylation data for VPS39-silenced myoblasts and controls at day 3 of differentiation (n=6 independent experiments).
ORGANISM(S): Homo sapiens 
2021-02-11 | GSE166587 | GEO
TranscriptomicsmRNA expression data for VPS39-silenced human muscle cells and controls
mRNA expression data for VPS39-silenced human muscle cells and controls (n=6 per group) were obtained using GeneChip™ Human Gene 2.0 ST Assay (Applied Biosystems)
ORGANISM(S): Homo sapiens 
2020-12-14 | GSE157345 | GEO
UnknownNon-native fold of the putative VPS39 zinc finger domain.
Not available
S-EPMC7384125 | biostudies-literature
UnknownThe HOPS complex subunit VPS39 controls ciliogenesis through autophagy.
Not available
S-EPMC7158379 | biostudies-literature
UnknownRegulation of vacuole fusion in stomata by dephosphorylation of the HOPS subunit VPS39.
Not available
S-EPMC12716901 | biostudies-literature
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