Sort   by:  
 Page size 
MetabolomicsA metabolic dependency for host isoprenoids in the obligate intracellular pathogen Rickettsia parkeri underlies a sensitivity for the statin class of host-targeted therapeutics
Gram-negative bacteria in the order Rickettsiales are obligate intracellular parasites that cause human diseases such typhus and spotted fever. They have evolved a dependence on essential nutrients and metabolites from the host cell as a consequence of extensive genome streamlining. However, it rema...
2019-10-31 | MTBLS846 | MetaboLights
TranscriptomicsReplacing skeletal muscle alpha-actin with cardiac actin in mouse skeletal muscle
Skeletal muscle actin mice (Crawford et al., (2002) Mol Cell Biol 22, 5587) were crossed with cardiac actin transgenic mice (termed "ACTC^Coco" or "Coco" for short), to produce mice that had cardiac actin instead of skeletal muscle actin in their skeletal muscles (termed "AC...
ORGANISM(S): Mus musculus 
2009-05-24 | E-GEOD-12882 | biostudies-arrayexpress
ProteomicsNOD Mouse Islet Peptide Content Identification
Beta-cells produce hybrid insulin peptides (HIPs) by linking insulin fragments to other peptides through peptide bonds. HIPs have unique amino acid sequences and are targeted by autoreactive T cells in type 1 diabetes (T1D). Individuals with recent-onset T1D have significantly higher levels of HIP-r...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-16 | PXD041616 | Pride
Hips Nod mouse Islet cells Peptides Lc-msms 
TranscriptomicsRNA-seq of primary murine (C57BL/6J) LSK cells overexpressing miR-10a or miR-335
In this experiment, we want to assess the effect of a lentiviral miR-10a and miR-335 overexpression on the transcriptome of murine LSK (Lin-,Sca-1+,c-Kit+) cells. Primary LSK cells were transduced with lentiviral miRNA overexpression constructs (control: GFP overexpression) and sorted for transduced...
ORGANISM(S): Mus musculus 
2018-06-01 | E-MTAB-6496 | biostudies-arrayexpress
UnknownPreventing preventable strokes: A study protocol to push guideline-driven atrial fibrillation patient education via patient portal.
Not available
S-EPMC9596318 | biostudies-literature
UnknownBeneficial Effects of School-based Mindfulness Training On Impulsivity in Healthy Adolescents: Results From a Pilot Randomized Controlled Trial.
Not available
S-EPMC9678328 | biostudies-literature
TranscriptomicsRRP1B is a Metastasis Modifier that Regulates the Transcriptome through mRNA Splicing
RRP1B is a Metastasis Modifier that Regulates the Transcriptome through mRNA Splicing To assess the role of RRP1B in alternative mRNA splicing, we knocked down the expression of Rrp1b in the highly metastatic mouse mammary tumor cell line Mvt-1 using shRNA. Two control and two knockdown stable cell ...
ORGANISM(S): Mus musculus 
2014-06-08 | E-GEOD-38669 | biostudies-arrayexpress
UnknownA food system transformation pathway reconciles 1.5 °C global warming with improved health, environment and social inclusion.
Not available
S-EPMC12716996 | biostudies-literature
GenomicsChIP-seq to identify the positions of three histone modifications in the rice genome
Gene expression is controlled by the complex interaction of transcription factors binding to promoters and other regulatory DNA elements. One common characteristic of the genomic regions associated with regulatory proteins is a pronounced sensitivity to DNase I digestion. We generated genome-wide ...
ORGANISM(S): Oryza sativa 
2011-11-09 | E-GEOD-26733 | biostudies-arrayexpress
UnknownGenomic characterization of the C. tuberculostearicum species complex, a prominent member of the human skin microbiome.
Not available
S-EPMC10790575 | biostudies-literature
Sort   by:  
 Page size