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UnknownTwo induced pluripotent stem cell (iPSC) lines derived from patients affected by Waardenburg syndrome type 1 retain potential to activate neural crest markers.
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S-EPMC10240564 | biostudies-literature
TranscriptomicsMicroarray analysis of RNA stability in mouse Neuro-2A cells
Microarray analysis of RNA stability in mouse Neuro-2A cells
ORGANISM(S): Mus musculus 
2011-01-24 | E-MTAB-952 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of RNA stability in mouse Neuro-2A cells
Cells were grown to ~50% confluency before RNA polymerase activity was blocked with 10 µg/mL Actinomycin D (Sigma) in DMSO. Control cells were treated with DMSO alone. Transcriptional inhibition of N2A cells was conducted for 32 h with cells harvested at time zero (0 h) and after 30 min, 2, 4, 8, 16...
ORGANISM(S): Mus musculus 
2012-01-24 | E-MTAB-961 | biostudies-arrayexpress
TranscriptomicsGene expression data from CNS-PNETs and various other brain tumor samples
Primitive neuroectodermal tumors of the central nervous system (CNS PNETs) are highly aggressive, poorly differentiated embryonal tumors occurring predominantly in young children. Using DNA methylation and gene expression profiling we have demonstrated that a significant proportion of institutionall...
ORGANISM(S): Homo sapiens 
2016-02-25 | E-GEOD-73038 | biostudies-arrayexpress
TranscriptomicsATAC-seq of Mus musculus embryonic cell types in response to Pbx1 knockout
ATAC-seq was performed, mapped, and analyzed as previously described (PMID: 34446717: \\"ATAC-seq was performed on 50,000 cells per replicate as described in Buenrostro et al. (with modifications based on Corces et al.), on EpiSCs and PSM-differentiated cell populations at desired time-points. Libra...
ORGANISM(S): Mus musculus 
2023-12-01 | E-MTAB-13407 | biostudies-arrayexpress
TranscriptomicsDNA methylation data from CNS-PNETs and various other brain tumor samples
Primitive neuroectodermal tumours of the central nervous system (CNS PNETs) are highly aggressive, poorly differentiated embryonal tumours occurring predominantly in young children. Using DNA methylation and gene expression profiling we have demonstrated that a significant proportion of institutiona...
ORGANISM(S): Homo sapiens 
2016-02-25 | E-GEOD-73801 | biostudies-arrayexpress
TranscriptomicsAn alternative, arginase-independent pathway for arginine metabolism in Kluyveromyces lactis involves guanidinobutyrase as a key enzyme
Most available knowledge on fungal arginine metabolism is derived from studies on Saccharomyces cerevisiae, in which arginine catabolism is initiated by releasing urea via the arginase reaction. Orthologs of the S. cerevisiae genes encoding the first three enzymes in the arginase pathway were cloned...
ORGANISM(S): Kluyveromyces lactis 
2014-07-16 | E-GEOD-56060 | biostudies-arrayexpress
TranscriptomicsTranscriptional response to tetanus vaccination in porcine PBMCs
Three groups of German Landrace piglets were vaccinated with tetanus toxoid. Transcriptome profiles of PBMC were analysed from blood samples taken 0, 2, 4, 8, 24 and 75 hours after a first vaccination and 0, 2, 4, 8, 24 and 75 hours as well as 14 d after a second vaccination on day 14. pair wise com...
ORGANISM(S): Sus scrofa 
2012-12-31 | E-GEOD-38602 | biostudies-arrayexpress
TranscriptomicsNext Generation Sequencing Analysis of Saccharopolyspora erytharea transcriptomes
We report the high-throughput profiling of saccharopolyspora erythraea life cycle in bioreactors. RNA was harvested at seven time-points from bioreactors, three points immediately before, one during and three following the metabolic switch (as evidenced by biomass cell dry weight). We prepared unstr...
ORGANISM(S): Saccharopolyspora erythraea 
2013-06-18 | E-GEOD-39722 | biostudies-arrayexpress
TranscriptomicsEffects of digested onion extracts on intestinal gene expression using rat intestine slices
Rat small intestine precision cut slices were exposed for 6 hours to in vitro digested yellow (YOd) or white onion extracts (WOd) that was followed by transcriptomics analysis. The digestion was performed to mimic the digestion that in vivo takes place in the saliva, stomach and small intestine. A m...
ORGANISM(S): Rattus norvegicus 
2016-09-29 | E-MTAB-5120 | biostudies-arrayexpress
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