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ProteomicsSmall-molecule inhibitors of CRISPR/Cas13 enable versatile control of RNA knockdown in mammalian cells
Abstract: CRISPR/Cas13 has emerged as a leading platform for carrying out RNA knockdown and editing experiments, and presents an attractive therapeutic alternative to DNA editing technologies. However, strategies to directly modulate its activity in a fast, reliable, and generalizable manner are lac...
ORGANISM(S): Homo sapiens (Human) 
2026-07-17 | PXD063296 | Pride
Crispr/cas13 Cas13 inhibitors Lwacas13a Hdx-ms 
GenomicsIntrinsic RNA targeting constrains the utility of CRISPR-Cas13 systems [Screen]
Intrinsic RNA targeting constrains the utility of CRISPR-Cas13 systems [Screen]
PRJNA837526 | ENA
GenomicsIntrinsic RNA targeting constrains the utility of CRISPR-Cas13 systems [RNA-seq]
Intrinsic RNA targeting constrains the utility of CRISPR-Cas13 systems [RNA-seq]
PRJNA837474 | ENA
GenomicsIntrinsic RNA targeting constrains the utility of CRISPR-Cas13 systems [RIP-seq]
Intrinsic RNA targeting constrains the utility of CRISPR-Cas13 systems [RIP-seq]
PRJNA837609 | ENA
GenomicsHighly multiplexed mRNA quantitation with CRISPR-Cas13
Highly multiplexed mRNA quantitation with CRISPR-Cas13
PRJNA1222449 | ENA
GenomicsCASowary: CRISPR-cas13 guide RNA predictor for transcript depletion
CASowary: CRISPR-cas13 guide RNA predictor for transcript depletion
PRJNA699563 | ENA
UnknownRNA editing with CRISPR-Cas13.
Not available
S-EPMC5793859 | biostudies-literature
UnknownStructure-guided discovery of ancestral CRISPR-Cas13 ribonucleases.
Not available
S-EPMC12165695 | biostudies-literature
UnknownStructures, mechanisms and applications of RNA-centric CRISPR-Cas13.
Not available
S-EPMC11375968 | biostudies-literature
UnknownIn silico optimization of RNA-protein interactions for CRISPR-Cas13-based antimicrobials.
Not available
S-EPMC9547417 | biostudies-literature
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