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ProteomicsHeLa Cells Cross-Linked In Vivo versus as a Lysate
HeLa Cells were cross-linked with PIR either in vivo or as a lysate.
ORGANISM(S): Homo sapiens (Human) 
2019-07-12 | PXD013063 | Pride
Pir cross-linker xl-ms 
ProteomicsStructural Analysis of a Prokaryotic Ribosome Using a Novel Amidinating Cross-Linker and Mass Spectrometry
The structure of the Escherichia coli ribosome, a 2.5 MDa ribonucleoprotein complex containing more than 50 proteins, was probed using the novel amidinating cross-linker diethyl suberthioimidate (DEST) and mass spectrometry. Peptide cross-links derived from this complex structure were identified at ...
ORGANISM(S): Escherichia coli 
2015-12-23 | PXD003381 | Pride
Amidination Dest E. coli Mass spectrometry Diethyl suberthioimidate Ribosome Protein cross-linking 
ProteomicsLarge-Scale Quantitative Cross-Linking and Mass Spectrometry Provides New Insight on Protein Conformational Plasticity within Organelles, Cells, and Tissues
Many proteins can exist in multiple conformational states in vivo to achieve distinct functional roles. These states include alternative conformations, variable PTMs, and association with interacting protein, nucleotide, and ligand partners. Quantitative chemical cross-linking of live cells, organel...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-12 | PXD058430 | Pride
M.musculus qxl-ms 
ProteomicsIdentify Yeast Proteasome Cross-links with Multiple Ion Fragmentation Methods
Use of EThcD, CID, HCD and high energy HCD to identify protein cross-links
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-06-18 | PXD018310 | Pride
Yeast Proteasome Cross-links 
ProteomicsLarge-Scale Quantitative Cross-Linking and Mass Spectrometry Provides New Insight on Protein Conformational Plasticity within Organelles, Cells, and Tissues
Many proteins can exist in multiple conformational states in vivo to achieve distinct functional roles. These states include alternative conformations, variable PTMs, and association with interacting protein, nucleotide, and ligand partners. Quantitative chemical cross-linking of live cells, organel...
ORGANISM(S): Homo sapiens (Human) 
2026-01-12 | PXD058435 | Pride
H.sapiens qxl-ms 
ProteomicsLarge-Scale Quantitative Cross-Linking and Mass Spectrometry Provides New Insight on Protein Conformational Plasticity within Organelles, Cells, and Tissues
Many proteins can exist in multiple conformational states in vivo to achieve distinct functional roles. These states include alternative conformations, variable PTMs, and association with interacting protein, nucleotide, and ligand partners. Quantitative chemical cross-linking of live cells, organel...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-12 | PXD058448 | Pride
M.mulsculus qxl-ms 
ProteomicsLarge-Scale Quantitative Cross-Linking and Mass Spectrometry Provides New Insight on Protein Conformational Plasticity within Organelles, Cells, and Tissues
Many proteins can exist in multiple conformational states in vivo to achieve distinct functional roles. These states include alternative conformations, variable PTMs, and association with interacting protein, nucleotide, and ligand partners. Quantitative chemical cross-linking of live cells, organel...
ORGANISM(S): Homo sapiens (Human) 
2026-01-12 | PXD058437 | Pride
H.sapiens qxl-ms 
ProteomicsLarge-Scale Quantitative Cross-Linking and Mass Spectrometry Provides New Insight on Protein Conformational Plasticity within Organelles, Cells, and Tissues
Many proteins can exist in multiple conformational states in vivo to achieve distinct functional roles. These states include alternative conformations, variable PTMs, and association with interacting protein, nucleotide, and ligand partners. Quantitative chemical cross-linking of live cells, organel...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-12 | PXD058490 | Pride
M.musculus qxl-ms 
MetabolomicsInfluence of early life exposure, host genetics and diet on the mouse gut microbiome and metabolome
Although the gut microbiome plays important roles in host physiology, health and disease, we lack understanding of the complex interplay between host genetics and early life environment on the microbial and metabolic composition of the gut. We used the genetically diverse Collaborative Cross mouse s...
2016-10-05 | MTBLS345 | MetaboLights
UnknownElbow conditions: research priorities setting in partnership with the James Lind Alliance.
Not available
S-EPMC9685230 | biostudies-literature
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