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ProteomicsA Rab1 interactome illuminates its dual role in autophagy and membrane trafficking
The small GTPase Rab1 is found in all eukaryotes and acts in both ER-to-Golgi transport and autophagy. Several Rab1 effectors and regulators have been identified, but the mechanism by which Rab1 orchestrates these distinct processes remains incompletely understood. We apply MitoID, a proximity bioti...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-05 | PXD070863 | Pride
Crosslinking Sda 
TranscriptomicsCross-platform comparability of microarray data
To facilitate collaborative research efforts between multi-investigator teams using DNA microarrays, we identified sources of error and data variability between laboratories and across microarray platforms and methods to accommodate this variability. RNA expression data were generated in seven labo...
ORGANISM(S): Mus musculus 
2010-06-10 | E-GEOD-2458 | biostudies-arrayexpress
ProteomicsA cryo-EM structure of metazoan TRAPPIII, the multisubunit complex that activates the GTPase Rab1
The TRAPP complexes are nucleotide exchange factors that have essential roles in membrane traffic and autophagy. TRAPPII activates Rab11, and TRAPPIII activates Rab1, with the two complexes sharing a core of small subunits that affect nucleotide exchange, but being distinguished by specific large su...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-06-03 | PXD025064 | Pride
Exchange factor / rab1 / autophagy / membrane traffic / golgi 
TranscriptomicsTranscription profiling of brain and spleen from rhesus macaque to validate two oligonucleotide array
We constructed a database containing 248,000 exon sequences from 23,000 human RefSeq genes and compared each human exon with its best matching sequence in the January 2005 version of the rhesus genome project list of 486,000 DNA contigs. Best matching rhesus exon sequences for each of the 23,000 hum...
ORGANISM(S): Macaca mulatta 
2007-01-10 | E-TABM-189 | biostudies-arrayexpress
TranscriptomicsA Comparison of microarray and MPSS Technology Platforms for Expression Analysis of Arabidopsis
A comparison of microarray and MPSS technologies can help to establish the metrics for data comparisons across these technology platforms and determine some of the factors affecting the measurement of mRNA abundances using different platforms. Here, different Treatments/Conditions based on differen...
ORGANISM(S): Arabidopsis thaliana 
2007-09-14 | E-GEOD-8994 | biostudies-arrayexpress
UnknownCu-NHC Complex for Chan-Evans-Lam Cross-Coupling Reactions of <i>N</i>-Heterocyclic Compounds and Arylboronic Acids.
Not available
S-EPMC12889171 | biostudies-literature
UnknownGlobal metabolic profiling to model biological processes of aging in twins.
Not available
S-EPMC6974708 | biostudies-literature
ProteomicsProteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet
Pancreatic islets are essential for maintaining physiological blood glucose levels, and declining islet function is a hallmark of type 2 diabetes. Here we employ mass spectrometry (MS)-based proteomics to systematically analyse purified islets from 9 genetic or diet-induced mouse models representing...
ORGANISM(S): Mus musculus (Mouse) 
2021-10-08 | PXD024522 | Pride
Pancreas Alpha cells Beta cells Islets Library Proteome 
UnknownIdentification of cross-reactive allergens in cashew- and pistachio-allergic children during oral immunotherapy.
Not available
S-EPMC7716697 | biostudies-literature
TranscriptomicsExpression data from fully-expanded leaflet of Bambara groundnut genotype (S19-3)
Low temperature stress in a number of African countries, such as Botswana, at night can effect the growth and development of bambara groundnut, leading to losses in potential crop yield. Therefore, we made an attempt to identify and analyze the genes and gene modules associated with low temperature ...
ORGANISM(S): Vigna subterranea 
2016-02-10 | E-GEOD-72255 | biostudies-arrayexpress
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