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ModelsGuisoni2016 - Cis-regulatory system (CRS) can drive sustained oscillations
Guisoni2016 - Cis-regulatory system (CRS) can drive sustained oscillations This model is described in the article: Promoters Architecture-Based Mechanism for Noise-Induced Oscillations in a Single-Gene Circuit. Guisoni N, Monteoliva D, Diambra L. PLoS ONE 2016; 11(3): e015...
2016-11-03 | MODEL1611030000 | BioModels
ProteomicsIn-depth proteomic analysis of nasal fluids from patients with chronic rhinosinusitis and nasal polyps by data-independent acqusition
Antibiotics are commonly prescribed to treat chronic rhinosinusitis (CRS). However, the effects of antibiotics on the microbiome and secreted proteome remain unknown in regard to CRS.We analyzed the effects of antibiotics on the nasal secreted proteome inthe context of CRS using data-independent acq...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD018960 | Pride
Human Crs Nasal fluids Data independent acqusition 
GenomicsCombinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells
Hundreds of Chromatin Regulators (CRs) control chromatin structure and function by catalyzing and binding histone modifications, yet the rules governing these key processes remain obscure. Here, we present a systematic approach to infer CR function. We developed ChIP-string, a meso-scale assay that ...
ORGANISM(S): Homo sapiens 
2011-12-23 | E-GEOD-32509 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression in chronic rhinosinusitis
Increasing evidence suggests that CRS is a heterogeneous group of sinus disorders involving overlapping but distinct disease entities.The factors leading to different CRS phenotypes remain enigmatic. The role of miRNAs in the regulation of immunological and inflammatory processes is beginning to eme...
ORGANISM(S): Homo sapiens 
2011-12-08 | E-GEOD-32300 | biostudies-arrayexpress
GenomicsTNF-blockade attenuates the proinflammatory CRS signature of monocyte-derived macrophages.
TNF-blockade attenuates the proinflammatory CRS signature of monocyte-derived macrophages.
PRJNA1477156 | ENA
TranscriptomicsMonocyte-derived IL-1 and IL-6 are differentially required for cytokine release syndrome and neurotoxicity by CAR-T cells.
Single-cell transcriptome profiling using a 3' droplet-based platform (Chromium,10x Genomics) of human CD45+ leukocytes isolated from leukemic HuSGM3 mice infused with CD19.28z CAR-T cells, two days after cytokine release syndrome (CRS) onset and 5 days later.
ORGANISM(S): Homo sapiens 
2018-05-24 | E-MTAB-6505 | biostudies-arrayexpress
TranscriptomicsTNF-blockade attenuates the proinflammatory CRS signature of monocyte-derived macrophages.
TNF-blockade abates cytokine release, weight loss and eventual lethality in our preclinical model of CAR T cell-induced Cytokine Release Syndrome (CRS). Macrophages are known mediators in the pathophysiology of CRS. We generated this single-cell RNA sequencing data set to assess the effect of TNF on...
ORGANISM(S): Mus musculus 
2026-08-21 | GSE335046 | GEO
GenomicsPanicum hallii cultivar:CRS.3.G3
Panicum hallii CRS.3.G3 Transcriptome - CRS.3.G3.L_PacBio
PRJNA1360094 | ENA
GenomicsPanicum hallii cultivar:CRS.3.G3
Panicum hallii CRS.3.G3 Transcriptome - CRS.3.G3.L_Illumina
PRJNA1360115 | ENA
GenomicsPanicum hallii cultivar:CRS.3.G3
Panicum hallii CRS.3.G3 Transcriptome - CRS.3.G3.P_Illumina
PRJNA1360313 | ENA
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