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GenomicsE2F7 represses a transcriptional network of oscillating cell cycle genes to control S-phase progression.
E2F transcription factors are known to be important for timely activation of G1/S and G2/M genes required for cell cycle progression, but transcriptional mechanisms for deactivation of cell cycle regulated genes are unknown. Here, we show that E2F7 is highly expressed during mid to late S-phase, occ...
ORGANISM(S): Homo sapiens 
2012-01-04 | E-GEOD-32673 | biostudies-arrayexpress
TranscriptomicsS phase and HU profiles in wild-type and mutant cells
Total S phase was measured for wild-type cells undergoing meiS and mitS. Early replication origins were mapped in mitS in wild-type cells, and in meiS for wild-type, sml1 delete, rec8 delete and spo11 delete cells. Comparative genome hybridization was used to measure the kinetics and final extent of...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-18 | E-GEOD-35662 | biostudies-arrayexpress
TranscriptomicsReplication Timing in Yeast: CGH microarrays: S vs G1 cells in various stress conditions
Replication timing in Saccharomyces cerevisiae in various replication stress conditions using CGH microarrays of S vs G1 cells. Replication of the eukaryotic genomes follows a characteristic temporal program, with different regions replicating at different times in S phase. We describe a stochastic ...
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-08 | E-GEOD-32002 | biostudies-arrayexpress
TranscriptomicsHigh resolution Hi-C analysis in S. pombe reveals fundamental elements of genome architecture [microarray CGH]
Eukaryotic genomes are folded into three-dimensional structures that govern diverse hromosomal procsses. Studeis in Drosophila and mammals have revealed large self-associating tomological domains whose borders are enriched in cohesin/CTCF factors that are required for long-range intrations. Howeve...
ORGANISM(S): Schizosaccharomyces pombe 
2014-10-22 | E-GEOD-56847 | biostudies-arrayexpress
TranscriptomicsKaryotype analysis of S. cerevisiae chromosome replacement lines - alpha-type cells
The S. cerevisiae hybrid karyotypes were analyzed by array-CGH to identify small regions of duplication or homeologous chromosomal exchange occurring during the strain construction. alpha-type cells. S. cerevisiae vs. Chromosome replacement lines. Biological replicates: 1 control (S. bayanus), 11 Ch...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-25 | E-GEOD-12776 | biostudies-arrayexpress
TranscriptomicsVariations in stress sensitivity and genomic expression in diverse S. cerevisiae strains
This SuperSeries is composed of the following subset Series: GSE10267: Variations in stress sensitivity and genomic expression in diverse S. cerevisiae strains (CGH) GSE10268: Variations in stress sensitivity and genomic expression in diverse S. cerevisiae strains (gene expression) Keywords: SuperSe...
ORGANISM(S): Saccharomyces cerevisiae 
2008-09-05 | E-GEOD-10269 | biostudies-arrayexpress
TranscriptomicsS-phase time-course of Lachancea kluyveri cells
Haploid cells of Lachancea kluyveri were arrested in G1 phase using Saccharomices cerevisiae alpha factor. After, release in a new media, cells go synchronously through S-phase. One sample is taken every five minutes. Microarrays are used to monitor the change of DNA copy number from 1 to 2, all alo...
ORGANISM(S): Lachancea kluyveri 
2013-02-01 | E-GEOD-37244 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of Saccharomyces boulardii and Saccharomyces cerevisiae to determine genomic differences
A comparative genomic hybridisation experiment using Affymetrix YG-S98 arrays to study the genetic background of S. Boulardii compared to S. Cerevisiae strain BY4743. Background: Saccharomyces boulardii, a yeast that was isolated from fruit in Indochina has been used as a remedy for diarrhoea since ...
ORGANISM(S): Saccharomyces boulardii 
2006-11-10 | E-MAXD-15 | biostudies-arrayexpress
Transcriptomics3' RNA-Seq (3'SEQ) analysis gene expression profiling at G1-S transition in human embryonic stem cells (hESCs) and hESC-derived endoderm cells
In this report, we examine transcripts on a genome-wide level between the synchronized cell cycles of hESCs and hESC-derived endoderm cells. We found 10347, 10299 and 10362 genes expressed in the G1, G1/S, and S phase of hESCs, respectively; 10333, 10227 and 10215 genes expressed at the G1, G1/S and...
ORGANISM(S): Homo sapiens 
2014-05-14 | E-GEOD-47117 | biostudies-arrayexpress
TranscriptomicsKaryotype analysis of S. cerevisiae chromosome replacement lines - a-type cells
The S. cerevisiae hybrid karyotypes were analyzed by array-CGH to identify small regions of duplication or homeologous chromosomal exchange occurring during the strain construction. a-type cells. S. cerevisiae vs. Chromosome replacement lines. Biological replicates: 1 control (S. bayanus), 11 Chromo...
ORGANISM(S): Saccharomyces bayanus 
2010-06-25 | E-GEOD-12775 | biostudies-arrayexpress
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