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ProteomicsThe contribution of the transcription factors Crz1 and Rim101 to the response to alkalinization in Komagataella phaffii
In the industrially relevant yeast Komagataella phaffii, as in other yeasts, alkalinization of the medium results in fast and extensive transcriptional remodeling. This response has been useful to design novel methanol-free, regulatable platforms for heterologous protein expression. However, its mol...
ORGANISM(S): Komagataella phaffii 
2025-09-02 | PXD064682 | Pride
Lc-ms Crz1 Lfq 
GenomicsGenome-wide recruitment profiling of transcription factor Crz1 in response to high pH stress
Exposure of the budding Saccharomyces cerevisiae to an alkaline environment produces a robust transcriptional response involving hundreds of genes. Part of this response is triggered by an almost immediate burst of calcium that activates the Ser/Thr protein phosphatase calcineurin. Activated calcine...
ORGANISM(S): Saccharomyces cerevisiae 
2016-06-27 | E-GEOD-79342 | biostudies-arrayexpress
GenomicsTranscript levels of genes in both the wild type SN148 and the crz1/crz1 mutant with or without 0.2M CaCl2 treatment
Transcript levels of genes in both the wild type SN148 and the crz1/crz1 mutant with or without 0.2M CaCl2 treatment
PRJNA507600 | ENA
TranscriptomicsIdentification of calcineurin- and Crz1-dependent targets in Candida glabrata
In order to identify calcineurin pathway-regulated genes, we compared the genome-wide expression profile of wild-type with FK506-treated wild-type, cna1, and crz1 mutants. We expect that FK506-treated wild-type will have similar expression profile with that of the cna1 mutant. In response to calcine...
ORGANISM(S): Candida glabrata 
2011-08-31 | E-GEOD-31167 | biostudies-arrayexpress
GenomicsIdentification of calcineurin-dependent, Crz1-independent gene expression changes in response to chronic KCl stress
Identification of calcineurin-dependent, Crz1-independent gene expression changes in response to chronic KCl stress
PRJNA1071034 | ENA
GenomicsIdentification of calcineurin-dependent, Crz1-independent gene expression changes in response to chronic CaCl2 stress
Identification of calcineurin-dependent, Crz1-independent gene expression changes in response to chronic CaCl2 stress
PRJNA1071031 | ENA
GenomicsGenome-wide recruitment profiling of transcription factor Crz1 in response to high pH stress
Exposure of the budding Saccharomyces cerevisiae to an alkaline environment produces a robust transcriptional response involving hundreds of genes. Part of this response is triggered by an almost immediate burst of calcium that activates the Ser/Thr protein phosphatase calcineurin. Activated calcine...
ORGANISM(S): Saccharomyces cerevisiae 
2016-06-27 | GSE79342 | GEO
UnknownMolecular Dissection of Crz1 and Its Dynamic Subcellular Localization in Cryptococcus neoformans.
Not available
S-EPMC9963361 | biostudies-literature
TranscriptomicsTranscript levels of genes in both the wild type SN148 and the crz1/crz1 mutant with or without 0.2M CaCl2 treatment
We report the expression levels of transcripts for two alleles of 6,211 genes in log-phase growing cells of the wild type SN148 and the crz1/crz1 with or without 0.2M CaCl2 treatment.We find that as compared to the wild type cells without 0.2M CaCl2 treatment, there are 828 genes upregulated in the ...
ORGANISM(S): Candida albicans 
2018-11-30 | GSE123122 | GEO
TranscriptomicsExtensive rewiring of the Calcineurin-Crz1 stress response network in the human fungal pathogen Cryptococcus neoformans
Calcineurin is a highly conserved Ca2+/calmodulin-dependent serine/threonine-specific protein phosphatase that orchestrates cellular Ca2+ signaling responses. In Cryptococcus neoformans, calcineurin is activated by multiple stresses including high temperature, and is essential for stress adaptation ...
ORGANISM(S): Cryptococcus neoformans H99 
2017-04-07 | GSE93005 | GEO
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