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ProteomicsCsrA-controlled proteins important for Acinetobacter baumannii desiccation tolerance
Hospital environments serve as excellent reservoirs for the opportunistic pathogen Acinetobacter baumannii in part because it is exceptionally tolerant to desiccation. To understand the functional basis this trait, we used transposon sequencing (Tn-seq) to identify genes contributing to desiccatio...
ORGANISM(S): Acinetobacter baumannii AB5075 
2022-10-13 | PXD028391 | Pride
Acinetobacter baumannii Intrinsically disordered proteins Csra Desiccation Tn-seq 
TranscriptomicsCLIP-seq of CsrA foci in Enteropathogenic E. coli
The RNA content of the CsrA foci. EPEC (E2348/69 (strain O127:H6)) expressing CsrA-FLAGx3-GFP or wild-type EPEC expressing untagged CsrA (negative control) were grown to OD 0.6 in DMEM and subjected to the foci-enrichment protocol, followed by RNA extraction and library preparation. Six libraries we...
ORGANISM(S): Escherichia coli O127:H6 str. E2348/69 
2025-04-14 | E-MTAB-14951 | biostudies-arrayexpress
ProteomicsProteomics identification of CsrA-regulated proteins in Legionella pneumophila
The carbon storage regulator protein CsrA regulates cellular processes post-transcriptionally by binding to target-RNAs altering translation efficiency and/or their stability. In this dataset we identified proteins regulated by CsrA in the human bacterial pathogen Legionella pneumophila by labelfree...
ORGANISM(S): Legionella pneumophila str. Paris 
2017-02-13 | PXD004730 | Pride
Labelfree shotgun proteomics Legionella pneumophila Csra 
TranscriptomicsThe interplay between a protein and an mRNA antagonist controls CsrA-mediated regulation of flagella genes in Campylobacter jejuni
This study investigates the CsrA regulon of the food-borne pathogen Campylobacter jejuni. Direct RNA binding targets of CsrA in two strains of C. jejuni, NCTC11168 and 81-176, were determined using RIP-seq. Identification of CsrA binding sites in two C. jejuni strains using RIP-seq
ORGANISM(S): Campylobacter jejuni subsp. jejuni 81-176 
2016-04-07 | E-GEOD-58419 | biostudies-arrayexpress
TranscriptomicsThe pyruvate-tricarboxylic acid cycle node: a focal point of virulence control in the enteric pathogen Yersinia pseudotuberculosis [csrA mutant]
Whole transcriptome assessment of the Yersinia pseudotuberculosis strain YPIII. The Y. pseudotuberculosis csrA regulon was determined in Yersinia minimal minimum developed for the study. CsrA is a key regulator coordinating virulence and metabolism. Y. pseudotuberculosis YPIII or the isogenic csrA m...
ORGANISM(S): Yersinia pseudotuberculosis 
2014-09-17 | E-GEOD-54545 | biostudies-arrayexpress
GenomicsCLIP-seq of CsrA foci in Enteropathogenic E. coli
CLIP-seq of CsrA foci in Enteropathogenic E. coli
PRJEB87337 | ENA
GenomicsDeciphering the regulatory role of CsrA in Leptospira biflexa
Deciphering the regulatory role of CsrA in Leptospira biflexa
PRJEB44661 | ENA
GenomicsLoss of CsrA in Acinetobacter baumannii leads to lethal dysregulation of alanine metabolism
Loss of CsrA in Acinetobacter baumannii leads to lethal dysregulation of alanine metabolism
PRJNA1387212 | ENA
UnknownComplex regulation of the global regulatory gene csrA: CsrA-mediated translational repression, transcription from five promoters by Eσ⁷⁰ and Eσ(S), and indirect transcriptional activation by CsrA.
Not available
S-EPMC3189700 | biostudies-literature
UnknownBinding of Campylobacter jejuni FliW Adjacent to the CsrA RNA-Binding Pockets Modulates CsrA Regulatory Activity.
Not available
S-EPMC7829508 | biostudies-literature
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