Sort   by:  
 Page size 
GenomicsFat body-specific reduction of CTPS alleviates HFD-induced obesity
Fat body-specific reduction of CTPS alleviates HFD-induced obesity
PRJNA915400 | ENA
TranscriptomicsFat body-specific reduction of CTPS alleviates HFD-induced obesity
High-fat diet (HFD)-induced obesity is a multi-factorial disease including genetic, physiological, behavioral, and environmental components. Drosophila has emerged as an effective metabolic disease model. Cytidine 5'-triphosphate synthase (CTPS) is a crucial enzyme for the de novo synthesis of CTP, ...
ORGANISM(S): Drosophila melanogaster 
2023-08-30 | GSE221707 | GEO
UnknownInterfilament interaction between IMPDH and CTPS cytoophidia.
Not available
S-EPMC6220823 | biostudies-literature
UnknownFat body-specific reduction of CTPS alleviates HFD-induced obesity.
Not available
S-EPMC10495109 | biostudies-literature
ProteomicsIdentification of CTPS1 Filament Interacting Proteins
CTP synthase (CTPS) catalyzes the formation of CTP in de novo pyrimidine biosynthesis pathway. Compartmentalization of CTPS into filamentous structure is evolutionarily conserved from E.coli, yeast, Drosophila, mice to humans. Recently, we have demonstrated that histidine-mediated protein methylatio...
ORGANISM(S): Homo sapiens (Human) 
2020-03-24 | PXD010921 | Pride
Snap29 Apex2 Ctps Cytokeratin 
TranscriptomicsHistidine-dependent protein methylation is required for compartmentalization of CTP synthase
CTP synthase (CTPS) forms compartmentalized filaments in response to substrate availability and environmental nutrient status. However, the physiological role of filaments and mechanisms for filament assembly are not well understood. Here, we provide evidence that CTPS forms filaments in response to...
ORGANISM(S): Homo sapiens 
2018-08-29 | GSE105251 | GEO
ProteomicsIdentification of CTPS1 Filament Interacting Proteins_2019 dataset
CTP synthase (CTPS) catalyzes the formation of CTP in de novo pyrimidine biosynthesis pathway. Compartmentalization of CTPS into filamentous structure is evolutionarily conserved from E.coli, yeast, Drosophila, mice to humans. Previously, we demonstrated that histidine (His) mediated methylation pro...
ORGANISM(S): Homo sapiens (Human) 
2020-03-24 | PXD015507 | Pride
Apex2 Tmt6 labeling Ctps1 Lc-ms/ms 
UnknownThe metabolic enzyme CTP synthase forms cytoskeletal filaments.
Not available
S-EPMC3210567 | biostudies-literature
UnknownHuman CTP synthase filament structure reveals the active enzyme conformation.
Not available
S-EPMC5472220 | biostudies-literature
UnknownAnalysis of the measurements used as potency tests for the 31 US FDA-approved cell therapy products.
Not available
S-EPMC11877884 | biostudies-literature
Sort   by:  
 Page size