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ProteomicsIdentification of CTPS1 partners
Identify CTPS1 partners obtained by immunoprecipitation of a GFP-CTPS1 fusion protein (N-terminal tag) expressed in the HEK 293T cell line.
ORGANISM(S): Homo sapiens (Human) 
2025-09-10 | PXD047654 | Pride
Gfp tag Hek Ctps1 
UnknownCTPS1 inhibition suppresses proliferation and migration in colorectal cancer cells.
Not available
S-EPMC9704378 | biostudies-literature
UnknownStructural basis for isoform-specific inhibition of human CTPS1.
Not available
S-EPMC8501788 | biostudies-literature
UnknownCTPS2 regulates CTP synthetase activity by interacting with CTPS1.
Not available
S-EPMC12442307 | biostudies-literature
UnknownDifferential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation.
Not available
S-EPMC10288033 | biostudies-literature
ProteomicsIdentification of CTPS1 Filament Interacting Proteins_2019 dataset
CTP synthase (CTPS) catalyzes the formation of CTP in de novo pyrimidine biosynthesis pathway. Compartmentalization of CTPS into filamentous structure is evolutionarily conserved from E.coli, yeast, Drosophila, mice to humans. Previously, we demonstrated that histidine (His) mediated methylation pro...
ORGANISM(S): Homo sapiens (Human) 
2020-03-24 | PXD015507 | Pride
Apex2 Tmt6 labeling Ctps1 Lc-ms/ms 
UnknownCTPS1 promotes malignant progression of triple-negative breast cancer with transcriptional activation by YBX1.
Not available
S-EPMC8734240 | biostudies-literature
UnknownImpaired lymphocyte function and differentiation in CTPS1-deficient patients result from a hypomorphic homozygous mutation.
Not available
S-EPMC7141395 | biostudies-literature
UnknownCombined inhibition of CTPS1 and ATR is a metabolic vulnerability in p53-deficient myeloma cells.
Not available
S-EPMC11460984 | biostudies-literature
UnknownCombined Inactivation of CTPS1 and ATR Is Synthetically Lethal to MYC-Overexpressing Cancer Cells.
Not available
S-EPMC9359733 | biostudies-literature
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