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ProteomicsAlteration of PFC proteome in MK-801 induced schizophrenia-like adolescent mice
Schizophrenia typically emerges in adolescence or early adulthood. Electrophysiological and several neurochemical changes have linked the GABA deficits to abnormal behaviors induced by NMDAR hypofunction. However, few studies have systematically investigated the molecular basis of GABA deficits, esp...
ORGANISM(S): Mus Musculus 
PXD035089 |
ProteomicsExtracellular Vesicle Biomarkers for Complement System Dysfunction in Schizophrenia
Schizophrenia has a high rate of misdiagnosis, leading to inappropriate or delayed treatment. Combining with extracellular vesicles’ (EVs) proteome profiling and XGBoost-based machine learning, we developed new pan-EVs markers and yielded personalized discrimination scores (PDS) for schizophrenia di...
ORGANISM(S): Homo Sapiens 
2023-02-20 | PXD040261 |
ProteomicsSystematic Proteomics Revealed The mechanism of How Long-term Tibetan Buddhist Meditation Enhanced Cardiovascular Protection
The difficulty to obtain data from whom uninterruptedly practice meditation over many years, and lacking of advanced analysis methods significantly hinder the comprehensive understanding of molecular mechanisms underlying meditation. This study aimed to address this issue.Accordingly, we recruited 8...
ORGANISM(S): Homo Sapiens 
PXD057418 |
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