We have found that the USP37 deubiquitylase binds to the DNA helicase known as CMG (Cdc45-Mcm-GINS) in mammalian cells. CMG unwinds the parental DNA duplex during the process of chromosome duplication, and USP37 is important to help cells survive problems in DNA replication.In this project, we inve...
ORGANISM(S): Mus musculus (Mouse)
