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MetabolomicsOral dysbiosis initiates periodontal disease in experimental kidney disease

BACKGROUND AND HYPOTHESIS: It is presently unclear why there is a high prevalence of periodontal disease in individuals living with chronic kidney disease. Whilst some have argued that periodontal disease causes chronic kidney disease, we hypothesized that alterations in saliva ...

2025-09-04 | MTBLS1833 | MetaboLights
TranscriptomicsTranscription profiling of Xenopus pronephric explants in presence or absence of hedgehog
Pronephric explants were dissected in the presence or absence of hedgehog signaling. Targets from pooled biological samples were examined in triplicate and the expression profiles were determined using Affymetrix Xenopus Genechip 1 arrays. Experiment Overall Design: 3 bhh treated pooled explants an...
ORGANISM(S): Xenopus laevis 
2008-06-12 | E-GEOD-3712 | biostudies-arrayexpress
TranscriptomicsMyelodysplastic syndrome: NUP98-HoxD13 (NHD13) expression effect on hematopoietic stem cells
Analysis of Lin-c-Kit+Sca-1- haematopoietic stem cells (HSCs) expressing the Nup98-HoxD13 (NHD13) fusion gene. NHD13 induces myelodysplastic syndrome (MDS) in mice. Results provide insight into the molecular basis of the myelodysplastic phenotype WT mouse HSCs were compared to an NHD13 mutant sequen...
ORGANISM(S): Mus musculus 
2016-07-03 | E-GEOD-66264 | biostudies-arrayexpress
UnknownAlmond Snacking for 8 wk Increases Alpha-Diversity of the Gastrointestinal Microbiome and Decreases Bacteroides fragilis Abundance Compared with an Isocaloric Snack in College Freshmen.
Not available
S-EPMC6736066 | biostudies-literature
UnknownWhy are epilepsy mortality rates rising in the United States? A population-based multiple cause-of-death study.
Not available
S-EPMC7449302 | biostudies-literature
UnknownAssociations Among 25-Hydroxyvitamin D Levels, Lung Function, and Exacerbation Outcomes in COPD: An Analysis of the SPIROMICS Cohort.
Not available
S-EPMC7118244 | biostudies-literature
TranscriptomicsSingle cell RNA-sequencing of PBMC derived B cells from human healthy donor
Motivation: The B-cell receptor (BCR) performs essential functions for the adaptive immune system including recognition of pathogen-derived antigens. The vast repertoire and adaptive variation of BCR sequences due to V(D)J recombination and somatic hypermutation (SHM) necessitates single-cell charac...
ORGANISM(S): Homo sapiens 
2018-06-22 | E-MTAB-6386 | biostudies-arrayexpress
ProteomicsA systems immunology study comparing innate and adaptive immune responses in adults to COVID-19 mRNA (BNT162b2/mRNA-1273) and adenovirus vectored vaccines (ChAdOx1-S)
We longitudinally profiled plasma proteomes in 54 adults vaccinated with the BNT162b2 (Pfizer-BioNTech) or ChAdOx1-S (Oxford-AstraZeneca) vaccines. Blood was collected pre-vaccination (V0) and 1-7 days after the 1st doses (BNT162b2 or mRNA-1273, V1) to assess innate and early adaptive responses. We ...
ORGANISM(S): Homo sapiens (Human) 
2023-03-01 | PXD036608 | Pride
Sars-cov-2 Proteomics Plasma Vaccination Covid-19 vaccine 
UnknownPilot Safety and Feasibility Study of Non-invasive Limb Proprioceptive Cerebellar Stimulation for Epilepsy.
Not available
S-EPMC8415900 | biostudies-literature
UnknownPeriprocedural Risk and Survival Associated With Implantable Cardioverter-Defibrillator Placement in Older Patients With Advanced Heart Failure.
Not available
S-EPMC7097837 | biostudies-literature
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